标签： 上海后花园 爱上海

The limited time price of Buick LaCrosse 2025 Platinum is 159,900-189,900 yuan.

New carOn October 30th, the 2025 Platinum model was officially launched, and the new car launched two models, the 28T Platinum Edition and the Platinum Edition Avia, with the price range of 209,900-239,900 yuan and the limited-time price of 159,900-189,900 yuan. At the same time, the new car also introduced a user rights replacement ceremony: up to 25,000 yuan (the national trade-in subsidy is 15,000 yuan+the brand replacement subsidy is as high as 10,000 yuan).


Official price of Buick 2025 platinum model car make and model Guide price (ten thousand yuan) Time-limited bite price (ten thousand yuan) 28T platinum edition 20.99 15.99 Platinum version of Avia 23.99 18.99 Watchmaking: Internet Info Agency


In terms of appearance, Buick LaCrosse 2025 Platinum continues the family design and adopts the PURE design concept. In the front face part, the large-size mesh grille of the new car expands outward, and the interior of the mesh is decorated with decorative strips, and then it looks very atmospheric with twice fangs-type silver chrome-plated decoration. At the same time, the wing-ray LED adaptive matrix headlight has 15 independent illumination zones, supports 9 intelligent lighting modes, and has a pedestrian-friendly design to further improve driving safety. In addition, the Avia model is equipped with the exclusive color matching of the imperial blue body.


Viewed from the side, the side shape of the new car adopts a relatively simple design style, and the smooth body lines create a very slender visual effect. In addition, the new car is also decorated with chrome trim around the window, which is more fashionable with 19-inch aluminum alloy wheels. In the rear part, the new car continues the through taillight group, and the unique interior light group adopts the light effect of "Long Lin Wings", which is highly recognizable after lighting. In terms of body size, the length, width and height of the new car are 4996/1866/472mm and the wheelbase is 2905 mm.

In terms of interior, Buick LaCrosse 2025 platinum model adopts yacht-style design style, which looks very simple and fashionable as a whole. In addition, the suspended center console of the new car not only has a strong sense of design, but also can further expand the storage space. The 30-inch curved 6K screen is fully matched. In terms of configuration, the 30-inch cambered 6K screen has a resolution of 6008×934, built-in Qualcomm Snapdragon 8155 chip, equipped with eConnect Zhilian technology, and supports multi-instrument display mode, private voice customization and other functions. In addition, Apple CarPlay wireless mapping function is also standard.




In terms of seats, the new car is equipped with 3D floating comfortable seats. The front and rear seat cushions are 505mm and 482mm in length, respectively, and are covered with advanced perforated leather. In addition, the Avia version is also equipped with four King seats, and the seat headrest also has the exclusive logo of Avia. Moreover, the front and rear seats of the new car are equipped with ventilation, heating and massage functions.

In terms of assisted driving, Buick LaCrosse Platinum 2025 is equipped with eCruise intelligent assisted driving, which supports up to 14 L2 intelligent assisted driving functions, including ACC full-speed adaptive cruise, APA automatic parking assist system, LCC intelligent lane centering assistance and other functions. In addition, the new car is also equipped with 360 degrees and HD.

In terms of power, the new car is equipped with the eighth generation Ecotec 2.0T variable cylinder turbocharging and matched with the 9-speed HYDRA-MATIC intelligent gearbox. The maximum power reaches 174kW, reaching 350N·m, accelerating for 7.2 seconds at 0-100km/h, and the comprehensive working condition of WLTC is 6.99L

(Photo/Wen Du Jinyi)

The latest poll of the US 2020 election： Biden’s support rate is 9 percentage points ahead of Trump.

　　The latest poll of the US 2020 election shows that former Vice President Biden’s support rate is 9 percentage points ahead of current President Trump. (Source: Getty Images)

　　Overseas Network July 15th　With the approaching of the US presidential election in 2020, a joint poll conducted by NBC News and The Wall Street Journal recently showed that former Vice President Biden was 9 percentage points ahead of current President Trump.

　　According to NBC, The Wall Street Journal and other US media reports, according to the latest polls, former Vice President Biden leads Trump by 51% to 42% in the ranking of winning percentage with current US President Trump, which is the one with the greatest chance of winning among the current Democratic candidates.

　　In addition, Democratic Senator Bernie Sanders leads Trump by 7 percentage points; Elizabeth Warren, Democratic Senator of California, leads Trump by 5 percentage points; California Democratic Senator Kamala Harris leads Trump by 1 percentage point.

　　According to the report, the survey found that Biden’s support rate among African-American voters, female voters, suburban voters and independents is higher than Trump’s, while Trump has a higher support rate among male voters, white voters and white voters without college education.

　　The report pointed out that the survey was conducted from July 7 to 9, with an error of plus or minus 3.5 percentage points, and the respondents included 800 registered voters.

　　Biden served as the 47th vice president of the United States, and ran for the presidency of the United States twice in 1988 and 2008, both of which failed. On April 25, Biden officially announced his participation in the 2020 presidential election. In his campaign video, he said: "We are in a war to defend the soul of this country."

　　Sanders announced his participation in the 2020 US presidential election on February 19th this year. Three years ago, he had a fierce competition with Hillary Clinton in the Democratic primary, and finally lost by only 1%.

　　Warren officially announced his candidacy for the presidency on February 10th this year to change a country that she said was "manipulated by the rich". After announcing the campaign, she quickly attracted the attention of Trump’s re-election campaign team.

　　Harris announced his participation in the 2020 US presidential election on January 22nd this year. She used to be the district attorney of San Francisco and the attorney general of California. She emphasized this experience in her campaign speech, saying that her career has been focused on ensuring people’s safety, and her campaign slogan is "For the People".

　　As early as February 27th last year, Trump announced that he would participate in the 2020 presidential election, and appointed Brad Pascal, a social media expert and digital media director of his 2016 campaign team, as campaign manager to help him prepare for re-election. (Overseas network Yao Kaihong)

The general secretary of the two sessions pays attention to these three ＂new＂ in the crucial year of network observation

In the two sessions of the National People’s Congress in 2024, the General Secretary of the Supreme Leader visited the delegation three times, and had cordial exchanges with the delegates on future-oriented issues such as new quality productivity, new pollution control and new quality combat effectiveness, so as to guide the high-quality development of China in the new era.

New quality productivity is characterized by innovation, the key lies in high quality, and the essence is advanced productivity.

This year’s National People’s Congress, which is regarded as the new quality productivity that incites the high-quality development of China’s economy, has undoubtedly become one of the hottest keywords.

From "don’t ignore and abandon traditional industries" to "cultivate and expand emerging industries and build future industries ahead of schedule", from "fight hard on key core technologies" to "promote scientific and technological innovation and industrial innovation as a whole, and strengthen the transformation and application of scientific and technological achievements" … … This year’s two sessions, with the topic of "new quality productivity", the General Secretary of the Supreme Leader clarified the dialectical relationship between new quality productivity and traditional industries, pointed out the direction to open up the blocking points that bound the development of new quality productivity, and defined the methodology for developing new quality productivity according to local conditions.

Since the "new quality productivity" was first put forward in September last year, the General Secretary has talked about the reality and urgency of developing new quality productivity on many occasions: "Scientific and technological innovation has achieved new breakthroughs, and new quality productivity has been accelerated" and "developing new quality productivity is the inherent requirement and important focus of promoting high-quality development".

Looking at China, a number of high-end, intelligent and green new pillar industries have risen rapidly, and the "new three kinds" of electric vehicles, lithium batteries and photovoltaic products have performed brilliantly. The new quality productivity has shown strong potential in supporting China’s high-quality development.

Looking around the world, a new round of scientific and technological revolution and industrial transformation is reconstructing the global innovation map and reshaping the global economic structure. We are faced with both rare historical opportunities and severe challenges in tackling key technical problems.

Whether it is to boost confidence, promote economic recovery, or win strategic initiative in future development and international competition, all localities should adjust measures to local conditions, proceed from reality and start with innovation, so that new quality productivity can empower thousands of industries and create new advantages for development.

The treatment of new pollutants is related to people’s health and ecological environment safety, and it is a "new difficulty" that restricts the continuous and in-depth improvement of air, water and soil environmental quality.

Compared with conventional pollutants, new pollutants such as light pollution, "white" pollution and marine plastic particles have the characteristics of serious harm, hidden risk, difficulty in degradation and difficulty in emission reduction and substitution.

The general secretary has been paying attention to this topic for a long time. "It is very timely to propose new pollution control now." When attending this year’s joint meeting in Chinese People’s Political Consultative Conference, the general secretary said: "With new problems, we can’t say that we can rest our hands before the old problems are dealt with, and we must catch them simultaneously."

Once, in autumn and winter, some areas in northern China often suffered from large-scale severe smog, an environmental indicator of "PM2.5"seriousExceeding the standard has become a long-standing problem. For more than 10 years, it is with the courage to face up to the problem and the foresight to build a beautiful China that the General Secretary has vigorously promoted the comprehensive environmental management of mountains, rivers, fields, lakes, grass and sand in the whole society, which has led to today’s "long-term blue" and the historic, turning and overall transformation of China’s ecological civilization construction.

At the joint meeting, for the treatment of new pollutants, the general secretary gave a breakthrough path: to systematically promote ecological protection and repair and solve outstanding problems in the ecological environment with "reform ideas, technical strength, transformation methods and market means".

"The scenery should be long and eye-catching." As the General Secretary said, "People who have no long-term worries will have near worries", grasping old problems, giving consideration to new ones, "taking real actions and solving one thing is a little", and comprehensively implementing policies and treating both the symptoms and the root causes can lay a good green background for the high-quality development of China.

High-quality economic and social development requires the development of new quality productive forces; To build a world-class army, it is also necessary to upgrade the new combat effectiveness.

"Promote the efficient integration and two-way pull of new quality productivity and new quality combat effectiveness", "Create the growth pole of new quality productivity and new quality combat effectiveness" and "fully liberate and develop new quality combat effectiveness" … … At the two sessions this year, the Chairman of the Supreme Leader was in the delegation of the People’s Liberation Army and the Armed Police Force, focusing on comprehensively improving the strategic capabilities in emerging fields and building new quality combat effectiveness.makeFurther deployment.

Since presiding over the work of the Central Military Commission, President Xi has always attached great importance to the construction of our army’s combat effectiveness, clearly pointed out that it is the only fundamental standard to firmly establish combat effectiveness, and emphasized that the combat effectiveness standard should be implemented in the whole process and all aspects of army building.

In 2019, President Xi pointed out at the Military Work Conference of the Central Military Commission that it is necessary to strengthen the construction of new combat forces and increase the proportion of new combat forces. Since then, when he inspected the troops, he has repeatedly talked about strengthening the construction of new quality combat effectiveness. The Party’s Report to the 20th CPC National Congress clearly proposed to increase the proportion of new territory and new quality combat forces.

The key to new combat effectiveness lies in "newness". The new expansion of "new" in the space field, the new change of winning mechanism, the new mutation of science and technology, the new mode of weapons and equipment and so on.

Aiming at the future battlefield, President Xi gained an insight into the general trend of the world, grasped the opportunities of the times, and made a scientific decision to liberate and develop new combat effectiveness, which not only conformed to the trend of the times, but also responded to the changes of the times, showing a broad vision and containing far-reaching considerations for the integrated operation of strengthening the country and the army.

Born to the new, the quality is strong. Anchoring the goal of building the army for a hundred years, keeping up with the development of modern war forms, constantly updating ideas and concepts, boldly innovating and exploring the construction and application mode of new combat forces, and forging a winning teacher have a long way to go.

Be the first in the spring of the year, and do everything first. From new quality productivity to new pollution control, and then to new quality combat effectiveness, the course has been anchored. Let’s go to "new" together.

Problems encountered during ETC system switching？ Let’s look at the answer from the Shanghai Municipal Transportation Commission.

According to the news released by Shanghai on December 30, the Municipal Transportation Commission said that according to the unified deployment of the Ministry of Transport, at 0: 00 on January 1, 2020, the national expressway will be switched, and the "one network" operation will be officially implemented to fully realize the fast passage of provincial boundaries without stopping. At present, all the work in Shanghai is progressing in an orderly way, and it has entered the critical stage of the final sprint.

Recently, many citizens have reported that they have encountered problems in the process of expressway toll station traffic and ETC installation, and the Municipal Transportation Commission has sorted out the answers to some questions.

Q: Some citizens said that they can’t take the expressway several times a year, and they didn’t install ETC equipment. Is it impossible to take the expressway in the future?

A:Encourage vehicles to pass quickly by installing and using ETC. After the provincial toll station of expressway is cancelled, vehicles without ETC can also pass by collecting CPC card at the entrance of expressway and paying CPC card at the exit. However, vehicles installed with ETC can complete payment without stopping all the time, which is more efficient and conducive to promoting energy conservation and emission reduction. Therefore, from the perspective of convenience, energy saving and environmental protection, users are encouraged to give priority to the rapid passage of expressways through the installation and use of ETC. In addition, ETC users can also enjoy preferential policies for tolls.

In the future, there will be more and more ETC application scenarios, such as non-inductive payment in parking lots and gas stations in the city, and citizens can enjoy faster services.

Q: Many citizens have found that there are fewer mixed lanes (that is, manual +ETC) at toll stations, which has caused congestion. How will this situation be solved?

A:According to the requirements of the State Council, the popularization and application of ETC will be accelerated, and the utilization rate of ETC on expressways will reach over 90%. In order to ensure a smooth transition between the old and new systems, at least two mixed lanes have been reserved in the toll stations where conditions permit. However, the current utilization rate of ETC has not yet reached the requirements, and there are still many vehicles choosing mixed lanes during peak hours, so there is a phenomenon of queuing in mixed lanes.

In view of this phenomenon, the transportation department has improved the operation guarantee scheme of toll stations, sent additional guidance personnel to deal with all kinds of emergencies in time and ensure the traffic order of toll stations. To this end, the transportation department also called on drivers to install ETC equipment as soon as possible to ensure the smooth running of their vehicles.

Q: What if a non-ETC vehicle accidentally strays into the ETC lane?

A:Non-ETC vehicles are not allowed to pass through ETC lanes. If non-ETC vehicles mistakenly enter, they will be guided to mixed lanes by the staff.

The transportation department reminds that drivers should pay close attention to the signs before entering the toll station square. Generally, there is a striking ETC reminder sign about 1 km to the expressway toll station.

Artificial lanes or mixed lanes are mostly set on the right, and drivers should choose the corresponding lanes according to the actual situation.

Q: After the provincial toll station of expressway is cancelled, can I use mobile payment methods such as Alipay and WeChat to pay the toll?

A:Mobile payment is an effective supplement to cash payment. The cancellation of provincial toll stations on expressways will not affect the normal use of mobile payment, and users can still use mobile payment methods at toll stations that support mobile payment.

Q: Some ETC users have reported that ETC is installed, but the success rate of identification is unstable, and there are frequent situations of "jamming" and not lifting the pole.

A:After investigation, it was found that there were many reasons for the failure to identify:

(1) At present, the expressway toll collection system is in the stage of joint debugging, and the software and hardware of the system are not stable, which has a certain impact on the traffic efficiency.

(2) Some drivers failed to activate the ETC equipment in time, and the system could not be read even though the equipment was installed.

(3) the speed is too fast. The vehicle is driving too fast, and the system has no time to read the information.

(4) Lane ETC reading failure.

(5) Credit card arrears, card suspension and other reasons lead to unsuccessful deduction.

At present, the transportation department requires all expressway project companies to speed up the equipment debugging progress and strive to control the impact to a minimum; At the same time, each booth of the toll station is equipped with staff, and once the equipment is "stuck", the staff will deal with it in time.

Remind drivers again that during the use of ETC equipment, please complete the equipment activation as soon as possible. In addition, in case of "jam", check whether the card is loose due to vehicle bumps, and try again after re-plugging.

Q: How can I get the toll bill after canceling the provincial toll station of the expressway?

A:The way of obtaining toll invoices remains unchanged. Users who use ETC (or user card) to pay tolls can obtain electronic invoices through "Toll Road Toll Invoice Service Platform", namely "Ticket Stub" APP, applet and website (website: www.txffp.com); If users pay in cash, they can obtain paper bills for the paid fees at the export toll station.

Q: Some car owners report that the ETC customer service hotline is often busy and can’t get through, which affects the customer service satisfaction experience?

A:1. Traffic Card Company, as the ETC issuing and service organization in this city, has added 4000012319 customer service hotline this year, and at the same time, it has added resident customer service personnel to the original 12319 urban construction hotline to provide customers with consultation and after-sales service. Considering the surge of ETC users this year, in order to better provide ETC follow-up consultation, equipment replacement and other services, after equipment failure, we can go to 66 service agency outlets set up by transportation card company for equipment inspection and maintenance; Next year, the transportation card company has set out to establish an online service model to effectively improve the quality of user service and strive to improve the user service experience.

2. In case of arrears, audit, invalidation of bank debit account, etc., users will be issued with use restriction marks. In this case, users can contact the signing bank or consult through hotline, and unbind according to the relevant agreement signed with the signing bank, and generally go to the counter of the signing bank to unbind.

In addition, in case of problems such as deduction, the general bank will initiate the deduction within 24 hours after the user’s highway traffic consumption, and some banks will inform the user by SMS after initiating the deduction.

Common problems in the use of ETC

(1) Q: How to check whether ETC equipment works normally?

A: Reseat the card. After re-plugging the card and hearing the beep, the device is normal when "Charge Card" or "Amount" is displayed on the device screen. If failure information such as "Failure" is displayed, please go to ETC service outlets for detection.

(2) Q: Can ETC equipment be disassembled by itself?

A: No. ETC equipment has anti-disassembly function. Once it is disassembled or dropped by itself, it will not be used normally. You need to contact ETC service outlets to re-install and activate it.

(3) Q: What should I do if ETC equipment can be identified in some lanes and not in others?

A: If there are multiple toll stations or lanes that can’t pass smoothly, please go to ETC service outlets for ETC equipment testing.

(4) Q: How to repair damaged ETC equipment or cards?

A: Go to ETC service outlets. Bank co-branded cards must go to the issuing bank for maintenance, and other maintenance services can be handled at various ETC service outlets.

(5) Q: Can ETC equipment handled in other places be installed and maintained in Shanghai?

A: No. Due to different issuers, Shanghai ETC service outlets cannot provide services for ETC equipment issued by other provinces and cities.

(6) Q: Do ETC stored value cards have to be converted into charge cards?

A: ETC stored-value cards can still be used. If users need to convert it into a charge card, they can go to 66 offline outlets of the Communications Card Company and more than 400 one-stop outlets of banks. In the first quarter of next year, the transportation card company will launch an online processing mode, which is more convenient for users to handle.

(Original title: "During the switching of ETC system, the answer to the traffic question you care about is here! ",with deletion)

Chronic Diseases in Fast Pace —— An Underestimated Silent Killer

[Introduction]

Suffering from chronic diseases has become a daily routine in Chinese. According to the latest report of the World Health Organization, Chinese has17％Will die prematurely because of chronic illness, specifically, on average every10 secondsOne person suffers from cancer; Average per10 secondsOne person suffers from diabetes; Average per30 secondsAt least one person died of cardiovascular and cerebrovascular diseases. Despite the continuous progress of medical technology, the situation of major chronic diseases is still not optimistic: the incidence of cancer ranks first in the world; The incidence of cardiovascular diseases continues to rise: the mortality rate of chronic obstructive pulmonary disease far exceeds the world level and the number of patients is close.100 million: the diabetic population has exceeded100 millionAnd keep growing.

Chronic diseases are the silent killers lurking around us.

　

Overdrawn life-the status quo of chronic diseases

Chronic disease, full name of chronic non-communicable disease.

Chronic diseases pose a serious threat to Chinese’s health. According to the World Health Organization’s 2020 global survey report on chronic diseases, the proportion of deaths due to chronic diseases in China has reached.89％The total death population is close to93 millionThe proportion of premature death due to chronic diseases has reached an alarming rate.17％. This means that about one in five people will end their original life course early because of chronic diseases.

　

Figure 1 Current situation of chronic diseases in China

　"Long course of disease and usually slow progress" is a major feature of chronic diseases. The World Health Organization defines chronic diseases as "health problems that need to be managed continuously for several years or decades". In 2020, the average life expectancy in China is 77.8 years, but the average life expectancy in health is about 69.2 years. In other words, residents have roughly8.6 yearsThe time to live with illness.

Hypertension and diabetes, which we are familiar with every day, are all covered by chronic diseases. Among all chronic diseases, cardiovascular diseases cause the largest number of deaths from non-communicable diseases, resulting in17.9 millionPeople died, followed by cancer (9 million), respiratory diseases (3.9 million) and diabetes (1.6 million). These four types of diseases account for all deaths from non-communicable diseases.80％.

Major chronic diseases

Cancer, cardiovascular and cerebrovascular diseases, respiratory diseases, diabetes

In the summer of 2021, Zhou Ming, an employee of a big factory in a first-tier city and born in the 1980s, found himself suffering from liver cancer in his physical examination. After nearly a quarter of his liver was cut off by surgery, he chose to take only a few days off, dragging the unhealed incision and continuing to work without telling anyone in the company.

According to the latest statistics of the World Health Organization, there were 19.29 million new cancers in the world in 2020, including 4.57 million new cancers in China, accounting for 23.7% of the world, and the number of cancer deaths in China exceeded 3 million in 2020, all of which ranked first in the world.

　

Fig. 2 The prevalence rate increased in China from 1998 to 2007.

Middle-aged people like Zhou Ming are not alone. In the era of fast pace and high competition, high pressure and frequent staying up late seem to have become a tacit lifestyle popular among workers in the workplace and even academic dogs in colleges and universities.

In addition to the rising cancer incidence rate due to the aging society, the changes in living environment and lifestyle have also led to the signs of a younger cancer incidence rate in China, and the number of cancer patients aged 20-39 has increased significantly.Cancer is becoming a normal state of human life in the form of chronic diseases, but we don’t know how to deal with it.[3]

　

Cardiovascular and cerebrovascular diseases

　According to the data of National Cardiovascular Center, the prevalence of cardiovascular diseases in China is on the rise.

Calculate the number of patients with cardiovascular disease290 millionAmong them, there are 13 million stroke, 11 million coronary heart disease, 5 million pulmonary heart disease, 4.5 million heart failure, 2.5 million rheumatic heart disease, 2 million congenital heart disease and 270 million hypertension.

Since 2009, the mortality rate of cardiovascular diseases in rural areas has exceeded and continuously exceeded the urban level. In 2015, the mortality rate of cardiovascular diseases among rural residents was298.42/100,000Among them, the death rate of heart disease is 1.4479/100,000, the death rate of cerebrovascular disease is 1.5363/100,000; the death rate of cardiovascular disease of urban residents is 2.6484/100,000, of which the death rate of heart disease is 1.3661/100,000, and the death rate of cerebrovascular disease is 1.2823/100,000.

　

Figure 3 Estimated number of hypertensive adults in China

　

Figure 4 Crude death rate of heart disease in cities

Respiratory diseases

　COPD generally refers to chronic obstructive diseases. Although this term is unfamiliar to the public, COPD is the third leading cause of death in the world. In 2013, the number of deaths due to chronic obstructive pulmonary disease in China was much higher than that due to lung cancer in China.

According to the survey data of China Adult Lung Health Research (CPHS) in 2018, the prevalence rate of COPD in adults aged 20 and over is 8.6%, and it is as high as 13.7% in adults aged 40 and over.For the first time, it is clear that the number of patients with COPD in China is nearly 100 million. COPD has become a chronic disease with hypertension and diabetes, which constitutes a major disease burden. The mortality rate of COPD in China is much higher than the world average.

In our country, every2.5 minutesOne person died of COPD, which has the characteristics of high prevalence rate, high incidence rate, high disability rate, high mortality rate, high economic burden rate and low awareness rate.

Fig. 5 Comparison of prevalence of COPD between urban and rural areas in China

Chronic obstructive pulmonary disease (COPD) is called chronic obstructive pulmonary disease (COPD). In recent years, the prevalence rate has increased, and the death toll has exceeded that of lung cancer.

According to the statistics of the top ten major causes of death in some cities and rural areas in China, respiratory diseases (including lung cancer) account for the fourth cause of death in cities and the third in rural areas. Due to air pollution, smoking, physical and chemical factors caused by industrial economic development, biological factors inhalation and population aging, the incidence of respiratory diseases such as lung cancer and bronchial asthma has increased significantly in recent years, and chronic obstructive pulmonary disease remains high.

　

Diabetes

Back in 1980s, the national epidemiological survey showed that the prevalence rate of diabetes in China was only 0.67%. According to the regional data of national disease surveillance in 2010, the prevalence rate of diabetes among residents over 18 years old in China is 9.7%. By 2013, when China scholars and the Journal of the American Medical Association published their research, the number of diabetic patients in China had jumped from about 92.5 million in 2007 to.100 millionThe prevalence of diabetes is approaching.12％.

From 2000 to 2016, the number of diabetic patients in China increased from 55,167,473 to 89,783,100, with a growth rate of 62.7%. By 2016, nearly 90 million people in Chinese had diabetes. In 2016, 140,000 people died of diabetes, of which 51% were men.The average annual increase is 2.16 million cases, with an increase of 6,000 cases per day, an increase of 247 cases per hour and an increase of 4 cases per minute.

　

Figure 6 Top Ten Countries in the Number of Diabetes Patients Aged 20 -79

Fig. 7 Changes of incidence of diabetes in China.

Urban-rural comparison

Focusing on the comparison between urban and rural areas, the prevalence of chronic diseases shows a trend related to the degree of urbanization.

According to the vertical comparison of urban scale, from four types of rural areas to big cities, the prevalence of chronic diseases is on the rise with the improvement of urban development. This means that,It is precisely where the economy is more developed and medical resources are more concentrated that people are more likely to suffer from chronic diseases.

　

Fig. 8 Comparative map of chronic diseases prevalence between urban and rural areas in China.

　

Figure 9 Changes of Chronic Disease Mortality in Urban and Rural Areas

Behind the wealth-the cause of chronic diseases

With the economic prosperity of China, millions of Chinese have successfully "lifted out of poverty", but it is accompanied by a "rapid change" in epidemiology.

The Lancet, the world’s top medical journal, systematically analyzed the disease burden of China in the past 30 years in a paper. The paper shows that the burden of diseases in China is changing, especially infectious diseases, and the maternal and child mortality rates have dropped significantly. However, the chronic diseases, mainly cardiovascular and cerebrovascular diseases and cancer, have increased significantly, which has become the main cause of premature death in China.

There are also health risk factors that change with it. Hypertension, smoking, high-salt diet and outdoor air pollution are also the chief culprits of cardiovascular and cerebrovascular diseases and cancer. These bad habits are common and insignificant in life, but they unconsciously become a gray area, which spans the development process from "health" to "chronic disease".

　

:: dietary imbalance

Unreasonable dietary structure is an important factor to induce chronic diseases. According to the report of the World Health Organization, 4.1 million deaths can be attributed to excessive intake of salt/sodium every year, and 4.1 million lives are lost, which is equivalent to one fifth of the population of Beijing.

In the past 30 years, China has experienced a transition from the traditional dietary pattern to the western dietary pattern, with the consumption of grains and vegetables decreasing and the consumption of meat and packaged food increasing. With the continuous development and progress of the national economy, the sources of nutrients obtained by Chinese residents are more abundant, and the dietary quality has not been improved, but there is still a big gap between the overall dietary quality and the ideal dietary quality. This gap also leads to the huge challenge that people are still facing the rapid growth of chronic diseases such as obesity and hypertension while improving their living standards.

Zhang Bing, deputy director of the Institute of Nutrition and Health of China Center for Disease Control and Prevention, pointed out that a reasonable diet is an effective means to prevent chronic diseases and promote health. Although in recent years, the state and relevant organizations have been vigorously promoting the implementation of the three reduction policies (reducing oil, salt and fat). However, in the latest "Report on Nutrition and Chronic Diseases of China Residents (2020)" press conference, Li Bin, deputy director of the National Health and Wellness Commission, emphasized that the unhealthy lifestyle of residents is still widespread-the dietary fat energy supply ratio continues to rise, and rural areas have exceeded the recommended upper limit of 30% for the first time. The daily cooking salt and oil consumption per family is still much higher than the recommended value. Chinese’s various dietary indicators still inevitably exceed the standard.

　

Fig. 10 Chart of Dietary Structure Series

　

Irregular work and rest

Sleeping late, staying up late, insomnia … Bad work and rest habits have also spread to counties and cities with the continuous advancement of urbanization. The average sleep time in Chinese has also shrunk from 8 hours a hundred years ago to today’s.6.8 hours. For every modern person, a healthy and adequate sleep time is increasingly becoming a luxury.

According to the data of China Sleep Research Association, bad work and rest habits will lead to an increase in the risk of some serious chronic diseases, such as cancer, diabetes and heart disease.

　

Fig. 11 Regional Distribution of Late Sleeping Party in China in 2018

Figure 12 Staying up late in different cities of China in 2021.

It can be found that the causes of staying up late in first-tier cities focus on work and refreshing; Second-tier cities have a strong tendency to work and rest irregularly, and the cause may be due to the complicated behavior, which is not specifically pointed out; The causes of the population’s late sleep in third-tier cities may point more to the urban sleeping environment. In the horizontal comparison of young people staying up late between cities, the rate of young people staying up late in new first-tier cities and first-tier cities is over 70%, while the data in second-tier cities, third-tier cities and below are lower than the first two, but the rate of young people staying up late here is also over 60%.

When irregular work and rest becomes a tendency of a group, it is hard for us not to think about whether this is the detailed embodiment of the negative impact of urbanization and globalization in the fast-paced era, and how we can resist the spread of bad sleep environment from the perspective of individuals, groups and even society, so that the whole of China can sleep peacefully at night.

　

Lack of exercise

　The World Health Organization points out that every year there are1.6 million casesDeath can be attributed to lack of exercise,

For Chinese, people are becoming more and more accustomed to sitting, instead of stretching their legs and moving around. With the advancement of urbanization, the degree of professional labor of people of all ages is generally reduced, and it is more and more convenient to travel. The popularity of electronic products has led to a general increase in residents’ static life time, a decrease in energy consumption, and an imbalance between energy intake and energy expenditure, which directly leads to individual obesity and increases the risk of chronic diseases.

　

Figure 12 Leisure exercise of China residents.

　

Timely intervention-before suffering from chronic diseases

In fact,There is a "transition period" from a healthy state to a chronic disease.. It is also the state in this transitional period that determines whether an individual’s physical state returns to health or falls into the abyss of chronic diseases.

Taking the intervention of diabetes as an example, the pre-diabetic population is in a "transition period" from high-risk groups to diabetes. Pre-diabetes refers to people with impaired fasting blood glucose or abnormal glucose tolerance, but they do not meet the diagnostic criteria of diabetes. They have a high risk of illness, accounting for more than one-third of adults in China. If they are intervened through an appropriate lifestyle, they can be transferred to the normal glucose metabolism population; But if left unchecked, it will be followed by lifelong disease development.

Therefore, it is not only important but also necessary to intervene in time for people in transition. Grasping the transition period is to grasp the floodgate of the spread of chronic diseases.

　

Social forces-environmental improvement

　The control of diseases is not only the self-restraint of a certain group of people, but also the collective restraint of the whole society.

The World Health Organization has clearly pointed out that tobacco causes more than 7.2 million deaths every year (including deaths caused by exposure to second-hand smoke), and it is expected to increase significantly in the next few years. The personal behavior of tobacco use has also become an important issue in the field of public health because of its diffusion. With the arrival of Healthy 2030, the China Center for Disease Control and Prevention and the Tobacco Control Office jointly put forward the slogan "Healthy China must be a smoke-free China".

Thanks to the efforts of all parties in the tobacco control campaign, the adult smoking rate in China has also shown a good trend year by year.

　

Figure 13 National Adult Smoking Rate

Give priority to prevention and proceed from prevention.

The power of society is not only focused on tobacco control, but also committed to creating an all-round supporting environment. The National Health and Wellness Commission and relevant departments continue to take joint actions and promote in environmental governance, tobacco control, nutrition improvement, health education, physical fitness, medical care, etc., to build an all-round supporting environment and form a joint force for prevention and control.

　

Government power-macro planning

　We need to pay attention to the progress of chronic disease control and face up to the grim situation of chronic disease prevention and control. Fat group, second-hand smoke and unbalanced diet caused by less exercise … These seemingly very personal living habits have become a systematic project that needs public attention and government supervision when they are related to the health status of a huge population.

China Health Development Report 2030 attempts to outline a healthier and more comfortable blueprint for our future with indicators and plans covering from top to bottom. Now, with only nine years left before the goal, the development situation of chronic diseases is not optimistic-can we achieve this goal?

　

Figure 14

Whether it is social forces or government planning, the final specific behavior still has to be implemented by individuals.

In the Outline of Healthy China 2030 Plan, all indicators are also divided into advocacy indicators, anticipation indicators and binding indicators. Among them, only binding indicators are mandatory by the government. The big goals in the field of health are all non-binding indicators.

This means that everyone must take action on the way to Health 2030.

　

Authors: Li Xiaoxiao, Quan Yi, Ding Ruifan,

Instructor: Wu Xiaokun

School: South China University of Technology

Editor: Wang Jing

　

Data source:

[1] Li Chengfu; Liu Hongyan; Liang Ying; Henry Hui Wang; Li Qianhui, Study on International Comparison of Healthy Life Expectancy and Prediction of Healthy Life Expectancy in China [J], Journal of Demography, 2018,40(01)

[2] the harm of lack of sleep. China Sleep Research Association

http://www.zgsmyjh.org/ndjsp? id=156＃_np=107_1187

[3] National Cancer Center: The latest cancer report of China in 2019.

http://www.360doc.com/content/19/0130/00/52645714_812065860.shtml

[4] The Lancet, Mortality, Incidence and Risk Factors in China and Its Provinces from 1990 to 2017: Systematic Analysis of Global Disease Burden in 2017.

https://new.qq.com/cmn/20210106/20210106A0BJSW00.html

[5] Information of the annual meeting of chronic diseases in China.

[6] China Center for Disease Control and Prevention Nutrition Statistics Yearbook, National Death Monitoring System.

After 00, who are the ＂red vests＂ in Wuhan community after attending online classes to help residents buy food？

　　In Wuhan in March, cherry blossoms gradually opened. In previous years, the scene of pedestrians weaving failed to appear, and the streets seemed a little deserted. The hot scene has shifted to the online — — In the WeChat group of various communities, the news of purchasing materials is constantly screened. After receiving the news, community workers and volunteers go out to purchase materials and distribute them to the owners. These "red vests" walking through the silent streets are adding countless warmth to Wuhan.

　　With a vibrating arm, the responders gathered.

　　Purchasing daily necessities, which is usually a piece of cake, is not simple for Wuhan people today. The community needs to count the needs of one household in advance, and then send the purchase list to the supplier. The goods have arrived, and in order to prevent people from gathering, they have to be distributed in groups. Heavy work requires a lot of people to go smoothly.

　　On February 23rd, Publicity Department of the Communist Party of China and the Central Civilization Office launched the "Volunteer Service and Care Action" in Wuhan, and recruited volunteers throughout the city. More than 70,000 people signed up in one week.

　　Liu Fang, a resident of Tongqingge Community, Stadium Street, Jiang ‘an District, Wuhan City, was very happy when he saw the news that his application was approved on the platform on the 26th. "It is very practical to be able to do something at this critical time".

　　She is one of more than a dozen people who are busy at the gate of Tongqingge community these days. She and her companions are busy distributing the purchased living materials to the residents of the community. Dozens of large plastic bags filled with materials were piled up at the door. For the convenience of statistics, volunteers wrote numbers on the bags, and one number was a household.

　　"Solitaire" in the group has become a "homework" that Wuhan residents must do every day recently. Residents should add their own needs to the last message summarizing their needs, and then forward it to facilitate statistics.

　　Turn on volunteer Cai Fei’s mobile phone. The theme of this day is "Seasoning", steamed meat powder, fermented bean curd, soy sauce, and Laoganma, which every household must order. Volunteers have compiled 188 lists.

　　"These young volunteers are really good," resident He Xuexian said. "Thousands of messages, I think they are busy every day." He often sees volunteers discussing the omissions of the day’s work in the group in the early hours of the morning, and then starting to arrange work at 7: 00 the next morning. "I wonder where they are resting."

　　When the ordered materials arrive, the volunteers inform the owners to come down and pick them up. Six households are a group, and the next group will be notified after one group has picked them up. They will stay from 2: 30 pm to 8: 00 pm.

　　Some community residents didn’t sign up for volunteers. Seeing the busy figure of this group of people, they also volunteered to help.

　　Taofen saw that the staff in the community were very busy and offered to help, but she was rejected. But she didn’t leave, but has been waiting by. When the volunteers saw this, they gave her the task of checking the list. "Because there are many varieties of dishes today and there are many households involved, we will feel at ease if we can share a little with volunteers."

　　He Xuexian, a photography enthusiast, calls himself a volunteer supernumerary. When he is free, he takes some photos for the volunteers as a souvenir. "Neighborhoods encourage each other and have more positive things for each other."

　　Cai Fei said: "Although it is said to be free, we can’t let everyone complain about us after we finish it. Since we do it, we will do it well and make our neighbors satisfied. " Volunteers were welcomed in the community, and the owners spontaneously donated masks for their protection.

　　Unite, cooperate and help each other

　　According to Xiong Huijuan, secretary of the Party Committee of Qiaokou Public Opinion Community, after a community cadre was diagnosed with COVID-19, the community workers were "isolated and sick". In the most difficult time, only three people here could come to work. Send patients, register, and their phones keep ringing.

　　After the recruitment order of "Volunteer Service Care Action" was issued, more than 30 volunteers joined immediately, which greatly eased the pressure on community cadres.

　　Qiu Xiong, a 27-year-old tenant of the public opinion community, was going to return to his hometown Huanggang for the New Year on the 29th of the twelfth lunar month, but he stayed because the passage from Han was closed.

　　Previously, Qiu Xiong learned from the WeChat group that Wuhan had to urgently build two hospitals, Vulcan Mountain and Raytheon Mountain. He took several friends from the dormitory to Vulcan Mountain. "We didn’t even take clothes, just put on a dress, swept a few bicycles downstairs and left." Qiu Xiong said with a smile that they all felt exhausted after riding for more than four hours to reach their destination.

　　Qiu Xiong and several friends worked in Vulcan Mountain and Raytheon Mountain for two weeks, day and night, and didn’t rest for days and nights during the busiest time. He said: "The most tiring time is that I can fall asleep in the bathroom, but when I get to the construction site, I don’t feel sleepy at all."

　　After returning to the community from the construction site of Raytheon Mountain and resting at home for two days, he saw that the community was recruiting volunteers, and he signed up for the community again.

　　"I grew up in Wuhan, and many people from Wuhan helped me when I was young. Besides, I’m from Hubei. This matter was originally from our side. If I can do my part, I will do my part," Qiu Xiong thought for a moment and added, "I won’t lose a piece of meat and come back after eating a bowl of noodles."

　　A family took their children from other places to see a doctor in Wuhan, but they were stranded in Wuhan due to the need of epidemic prevention and control. After staying in a small hotel outside for a few days, they ran out of money and had to stay at a friend’s house. Zhang Zhang led the team members to send them materials donated by the owners and caring people. The hostess was surprised and moved when bags of materials were delivered. Zhang Zhang took out 1,000 yuan and said to her, "We just sterilized this money with alcohol, so take it first for a rainy day." The hostess’s eyes were red, and she sobbed and said, "I am really grateful to the people in this community. The neighbors know that our children are out of rice paste, so they sent them to us, as well as the children’s clothes."

　　Zhang Zhang said: "The things in the community are all trivial things for ordinary people, but they add up to great things. As long as the residents are satisfied, I think our work has been done."

　　Volunteer service after online classes

　　Zhang Anxin is the youngest volunteer in the main street community of caidian district. She is only 16 years old and is in the second year of senior high school. Every working day, Zhang Anxin finishes the online class in the morning and goes to the community to participate in volunteer service at noon.

　　Her mother, Zhang Xingrong, is a grid worker in the community. Since the outbreak, community work has doubled and she often works overtime until late at night. Zhang Anxin saw it in her eyes and was anxious in her heart. She told her family that she wanted to help and reduce the workload of the community.

　　Although young, I have a lot of work. Zhang Anxin is more agile than adults in making registration forms and checking the number of group purchases.

　　Yu Hanming, a volunteer from Yudai Huijingyuan, Zhongshan Community, Qiaokou District, is a 2018 student at the School of Flight, Beihang University. He is just 20 years old this year.

　　Early in the morning, Yu Hanming’s mobile phone became a hotline. Since community residents have never seen Yu Hanming, they only know that he is a volunteer who can help buy food. Therefore, after 00, "Xiao Yu" became the "Master Yu" in the residents’ mouths.　

　　For Yu Hanming, who has never cooked, it is still a difficult problem to identify the varieties of vegetables. In order to complete the task of buying food, he prepared a small notebook, and he recorded the needs of every household to buy food.

　　Yu Hanming said that volunteering not only enriched his life, but also gained a full sense of accomplishment and made him grow. "I may not have paid special attention to the things around me, but now I will take the initiative to ask people around me if they have any needs and what I can do to help others. I can be more patient and careful in the face of the problem than before, and solve it instead of escaping as before."

　　The energy of volunteers is gathering into a warm spring in the ordinary world. What they do may be just ordinary or trivial things, but it is a major event in life for community residents, and it is also a practical matter to maintain the normal operation of Wuhan. As a volunteer said: COVID-19 is ruthless, Wu Hanyou loves; Great love is boundless, and small love warms the heart. (Text/Kan Chunyu)

2025 JD.COM 618 Shopping Carnival： Summer Value Feast Opens Tmall 618 Activity When will Taobao 618 start？

　　With the approaching of summer, the JD.COM 618 Shopping Carnival in 2025, a high-profile annual event in the electric business community, is poised to bring consumers an unprecedented shopping feast with a strong preferential lineup and innovative gameplay. This time, JD.COM carefully planned to optimize the shopping experience in an all-round way, with a large number of spot goods with rich subsidies and novel gameplay, and committed to letting consumers enjoy the value and joy of shopping this summer.

　　The JD.COM 618 event was promoted in stages and orderly, bringing continuous surprises to consumers. At 8 o’clock on the evening of May 13th, the "Heart Shopping Season" was first launched. As a warm-up activity, it will last until May 28th. During this time, consumers can feel the atmosphere of the shopping festival in advance, choose their favorite products and lock in the offers in advance. Then, at 8 o’clock on the evening of May 31st, JD.COM 618 officially kicked off. At that time, massive and over-valued goods will be fully sold, and various preferential activities will be launched simultaneously, and a wonderful shopping spree will be staged soon.

　　At the beginning of the event, the most anticipated red envelope benefits hit hard. From May 13th, the JD.COM 618 red envelope was officially opened! Just open the JD.COM APP on your mobile phone and search for "Shopping Red Packet 999". You will get three chances to receive red packets every day, and this benefit will last until June 18th. For more than a month, you can harvest surprise red envelopes easily with your fingers. These red envelopes can be directly deducted from cash at the time of shopping settlement, which can save a lot of money whether you buy daily necessities or long-awaited big items.

　　At the same time, JD.COM also has state subsidies for different categories: search for "mobile phone 500" or "Apple mobile phone 886" in JD.COM APP to buy mobile phone tablet digital products, and you can enjoy the 500 yuan subsidy at the highest; Search for "home appliances special 818" to buy home appliances, and the maximum subsidy can reach 2000 yuan, so that consumers can buy high-quality goods at more affordable prices.

　　This time, JD.COM 618 achieved a comprehensive upgrade in gameplay and built a rich and diverse marketing matrix. In the basic gameplay, classic preferential activities such as "over 200 MINUS 20 coupons" and "cross-store full reduction" have returned strongly, and the incentives are even stronger. Consumers can easily enjoy direct reduction and exemption as long as they meet the conditions, whether they buy a single item or a combination of multiple items across stores, and these offers can also be superimposed, so that consumers can really spend small money and buy good things.

　　In addition, JD.COM has carefully created seven theme promotion days, including surprise day, super spike day, 10 billion subsidy day, super provincial special price day, super live broadcast day, PLUS member day and ten thousand stores spike day. These theme days span the heart shopping season and the official activity period of 618, and each theme day has its own characteristics. There are random discounts and mysterious benefits on surprise day; Super spike day hot goods are limited in time and low in price; On the 10 billion subsidy day, JD.COM invested a huge amount of money to subsidize goods; Super-provincial special day focuses on good things with high cost performance; Well-known anchors on Super Live Day bring exclusive coupons and sweepstakes; PLUS members enjoy exclusive discounts and preemptive rights; Thousands of stores kill seconds, and massive stores kill seconds synchronously. During the event, many stars and popular IP will also be strongly linked, bringing interesting interaction and rich prizes, making shopping full of surprises and joy.

　　Tmall 618 red envelope

　　You can get 618 red envelopes by searching for [Happy 2266] on mobile phone Taobao.

　　618 has activities not only in JD.COM, but also in Taobao Tmall, which provides consumers with red envelopes to collect. You can collect them every day according to the above method, and the red envelopes you receive can be superimposed and used.

　　The whole 618 activity is divided into four stages. At the beginning stage, the explosive goods are launched at a low price, and consumers can snap up popular new products at the first time; During the special period, sales promotion will be carried out by category in turn to meet the segmentation needs of different consumers; During the climax, all kinds of carnival, the preferential intensity reached its peak, and the benefits such as red envelopes, full reductions and discounts were covered in all directions; JD.COM app searches for [Shopping Red Packet 999] to get 618 red packets. During the return period, consumers who missed the previous activities will be given the last chance to pick up the missing items. Popular products will be replenished with affordable prices and sufficient inventory.

　　In terms of characteristic play, JD.COM is also full of highlights. The "Spike" channel launched activities such as Super Spike Day and Big-name Spike Day, which helped businesses to enhance their exposure and gave consumers more opportunities to snap up big-name good things at ultra-low prices. The innovative "State Subsidy × 10 Billion Subsidy" channel combines policy dividends with platform concessions to create a shopping feast with the largest annual concessions. Consumers can enjoy double subsidies when purchasing a variety of goods, and realize low-cost shopping on the whole network. The "Special Price" channel brings activities such as "50% discount on special weekend", "2 yuan postage" and "factory direct sale", so that consumers can enjoy the super-value shopping experience. The "Trial" channel has been upgraded, and JD.COM has invested billions of resources to implement the model of "try first and then buy" big-name explosive products, which not only reduces the shopping risk of consumers, but also helps brands to pull new promotions and achieve a win-win situation.

　　In 2025, JD.COM 618 will invite consumers to this affordable and interesting shopping feast with full sincerity and innovative gameplay. No matter what kind of consumers you are, you can find your own shopping fun here and start a summer shopping spree!

The cheapest Mazda CX-30 is coming, not just for the face value.

Low fuel consumption is in line with the car demand of many office workers. After all, what I think about on my way to and from work every day is definitely not power control, but saving money and ensuring basic transportation needs. The Mazda CX-30 introduced today is a small suv. Let’s take a look at it together.

First of all, from the appearance, the Mazda CX-30 front looks elegant and looks very atmospheric. Coupled with stylish and simple headlights, it meets the "taste" of young consumers. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, delayed closing and so on. Coming to the side of the car body, the size of the car body is 4395 mm * 1797 mm * 1545 mm. The car adopts hard-line lines, and the side circumference looks very young. With large-sized thick-walled tires, the shape is eye-catching. Looking back, the rear of the car echoes the front of the car from a distance, and the taillight style is relatively simple. Coupled with the unique exhaust pipe, the shape is relatively cold.

In terms of interior, the interior looks very simple, giving people a very fashionable and generous feeling. The steering wheel of the car is very in line with the interior style, and it is equipped with functions such as manual steering wheel up and down+front and rear adjustment, which gives people an impulse to control it. Let’s take a look at the central control. The car is equipped with an ordinary LCD central control screen, which makes the interior design quite layered and gives people an elegant feeling. Finally, let’s look at the dashboard and seats. The car is equipped with an exquisite dashboard, which looks very clean. The car uses leather seats, which are wide and thick and comfortable.

Mazda CX-30 is matched with an automatic manual transmission (AT) gearbox, with a maximum power of 116KW and a maximum torque of 202N.m, and its power performance is good.

The car is equipped with car networking, remote control key, rear wiper, engine start and stop, traction control (ASR/TCS, etc.), which fully ensures the convenience and comfort of the car experience.

The SUV has an atmospheric appearance, good spatial performance and high cost performance. I wonder if you are interested in it. If you are planning to buy a car, then the car above is worth considering.

One vaccine prevents 12 cancers？ Stop joking!

　　A "sky-high" vaccine that can prevent 12 kinds of cancers is said to be quietly popular among wealthy people.

　　Some media reported a few days ago that Hong Kong MDX Medical Group released the "DCV Cancer Vaccine", which can prevent more than 12 kinds of cancers, including prostate cancer, breast cancer and lung cancer, with an injection of 98,000 yuan.

　　And such a good thing? The reporter of Science and Technology Daily immediately connected Zhi Xiuyi, the director of science popularization propaganda department of China Anti-Cancer Association and Professor xuanwu hospital of Capital Medical University, to hear what he said.

　　Is it pseudoscience? Try these three "magic mirrors"

　　"What cancer can be cured? Judging from this advertisement, it can basically be judged to be pseudoscience. " Zhi Xiuyi told the Science and Technology Daily reporter that, if nothing else, as far as lung cancer is concerned, there are small cell lung cancer and non-small cell lung cancer; Non-small cell lung cancer includes squamous cell carcinoma, adenocarcinoma, squamous adenocarcinoma and large cell carcinoma; Some cancers are derived from epithelial cells, while others are derived from mesothelial cells … … It is impossible to prevent only one kind of lung cancer, let alone prevent 12 kinds of cancers together.

　　This characteristic of malignant tumor is called "heterogeneity" in academic circles, which can be roughly understood as that even if it is classified as the same tumor, it may be completely different. Some academic articles show that there are two kinds of heterogeneity: one is that the gene mutation of tumor cells of the same patient is different at different stages of tumor occurrence; The other is that different patients have the same tumor, but that "same" is not necessarily the same, just the same phenotype does not mean that the genotype is the same.

　　Zhang Xuemin, an academician of China Academy of Sciences, used a very vivid analogy to explain "heterogeneity" at an academic seminar. He said: The genome in the human body is like taking a disk and dropping it underground. No fragments are the same twice, and no two tumor patients have the same mutation. The human body has 3 billion base pairs, and it may not develop tumors if it is changed by tens of millions. The main problem in treating tumors is to find out which one is the driver mutation, so that targeted therapy can be possible. At present, scientists are using big data to find the most critical driving mutation genes (which can be understood as core components). According to clinical data and proportion, thousands of tumor driving genes have been found.

　　It can be seen that it is impossible to control the broad-spectrum WT1 gene only as mentioned in the product description of "DCV cancer vaccine" (assuming that the injected substance can control the gene first), and the so-called "universal gene" is totally false.

　　Therefore, "omnipotent, cure all diseases" is the first "mirror", especially for malignant tumors with complex mechanism, it is even more impossible to "take one enemy and ten".

　　"This kind of pseudoscience has another feature, and there are no specific research institutions and research events. If it is a real thing, there should be specific scientific research projects and scientific research results data, and the results should be displayed at international or domestic cancer conferences. " Zhi Xiuyi explained, "If it is clearly said that it is the work of a research institute or scientific research team of a certain university in the United States and a series of experimental studies have been carried out, then other teams of scientists should be able to verify this research, or introduce their research results and data at the ASCO meeting of the global cancer conference or the CSCO meeting of the domestic cancer conference."

　　However, the "DCV Cancer Vaccine" released by Hong Kong MDX Medical Group did not disclose any clinical trial data, how related clinical verification was promoted, the effect of the third phase of clinical research, whether relevant papers were published in academic journals, and which scientists and research teams participated in the research work. To put it bluntly, this achievement is like being produced out of thin air and cannot be traced back.

　　"Out of thin air, untraceable" is the second mirror, while "commercial manipulation and speculation for profit" is the third mirror.

　　"Although the production of a fake news is out of thin air, it must be driven by huge economic interests." Zhi Xiuyi said that the research and development and innovation of new anti-tumor drugs need a lot of money, especially in the clinical verification stage, which requires hundreds of millions of funds.

　　At this time, the methods of speculating the concept, raising the stock price, and financing have become a brilliant move for many capital players, and fake news has also become one of the springboard for them to "play" the capital market. As long as the sales performance and followers take the lead, this wave of operation may attract investment and become the so-called "model" of commercial manipulation. As some media have analyzed, its commercial essence is "cutting leeks".

　　Don’t let pseudoscience "fry" the tumor vaccine

　　This is a lie rumor about tumor vaccine, but "tumor vaccine" is a real new biotechnology in recent years.

　　People are familiar with: cervical cancer vaccine, hepatitis B vaccine and so on.

　　"In principle, the principle of preventive tumor vaccine is to prevent microbial infection from inducing tumors. For example, cervical cancer vaccine is to prevent polyoma virus; Hepatitis B vaccine is to prevent liver cancer; Prevent EB virus and nasopharyngeal carcinoma; Prevent Helicobacter pylori and prevent gastric cancer. " Li Zhongming, editor-in-chief of Contemporary New Vaccine (first edition), who once worked as a censor in the FDA of the United States, explained to the reporter of Science and Technology Daily: At present, preventive tumor vaccines must be related to microorganisms, and only therapeutic vaccines are targeted at tumors.

　　Focus! Tumor vaccine is divided into preventive and therapeutic, and injected into healthy people and tumor patients respectively.

　　Preventive tumor vaccine is only aimed at tumors caused by viruses and other microorganisms. Because it can clarify the formation mechanism of tumors, it can prevent them, and many vaccines have been put on the market.

　　Therapeutic tumor vaccine: At present, a tumor vaccine for prostate cancer has been marketed in the United States, and several therapeutic products are in the clinical trial stage.

　　Since therapeutic tumor vaccine is aimed at tumor patients and is therapeutic, why is it also called vaccine?

　　Li Hangwen, founder and CEO of Microorganism, a leading domestic tumor vaccine company, explained to the reporter of Science and Technology Daily that "tumor vaccine is actually a kind of immunotherapy. For example, we use mRNA to express tumor antigen. Tumor antigen is like a marker (wearing a red hat), which will remind and mobilize the police (immune system) to catch thieves, and the person wearing a red hat is a thief. Therefore, the immune system can find the thief according to the red hat and then attack the tumor. "

　　Because the principle that "portrait" makes the immune system know about tumor is consistent with the principle of vaccine, this immunotherapy method is also called "tumor vaccine".

　　"This is different from the way in which chemical drugs and antibody drugs introduce foreign aid. Tumor vaccines completely rely on the immune response generated by the human body to eliminate tumors. " Li Hangwen said that once immunotherapy is effective, it will generally not produce drug resistance, and the immune system will "intelligently follow up" until the tumor is beaten. Moreover, immunotherapy will produce immune memory, and when the human body encounters the same pathogen attack again, it will quickly produce immune response and eliminate the pathogen. With traditional methods, it is easy to produce drug resistance, and the tumor will "wander". If it recurs, it may be more dangerous.

New Year’s Walk to the Grass-roots Cliff Village： A New Vision of Cultural Tourism Integration

Content introduction:

Liangshan Yi Autonomous Prefecture in Sichuan was once one of the "three districts and three states" deep poverty areas in China. Nine years ago, the reporter photographed Atulier Village, a village located on an 800-meter cliff in Zhaojue County, deep in Daliangshan Mountain, also known as "Cliff Village". For more than nine years, the reporter recorded the changes there with a lens. Today (February 12th), "Going to the Grassroots in the Spring Festival", I will visit Cliff Village again with the reporters from the General Station.

On the way to Cliff Village along Panshan Highway, I heard that Cliff Village is building a "Valley of the Sky" cultural tourism project, which makes everyone on our reporting team full of expectations. Many people remember Cliff Village, but in those days, it was necessary to climb cliffs when entering and leaving the village. At first, it was a rattan ladder road made of branches and vines, and later, steel pipes were reinforced into a steel ladder road, and the unique geographical features also became the advantage of developing alpine tourism here.

At the first stop after entering Zhaojue, we decided to go to the ski resort to find a guide for this trip-Rabo, who is already a ski instructor. Rabo, born in 1994, is a native of Cliff Village. Nine years ago, it was Rabo who led us to climb the rattan ladder and entered Cliff Village for the first time. In 2016, after the story of Cliff Village was reported by us, tourism began to be developed here, and Labo signed a contract with a cultural tourism enterprise. Now, in addition to being a ski instructor, he also undertakes the functions of training villagers’ safety services and explaining reception.

In 2020, according to the national ex situ poverty alleviation and relocation policy, 282 households and 1,219 people in Cliff Village moved off the cliff one after another and lived in the buildings in the county. Living at the foot of the mountain, the industry is on the mountain.In order to help more people "stay stable, find jobs and gradually get rich", Cliff Village develops the village collective economy according to the industrial development plan of "combination of long and short, interaction of planting and breeding, and integration of agriculture, culture and tourism". Villagers rely on land transfer, planting olives, navel oranges and raising sheep to increase their income. Today, the annual per capita disposable income of Cliff Village is more than 19,600 yuan, and the collective shares in tourism are nearly 10 million yuan. On the eve of the Spring Festival, local villagers were organized to return to Cliff Village, ready to give priority to recruiting local villagers to work in the "Sky Valley" cultural tourism project.

Now, the first phase of "Sky Valley" has been put into trial operation, steel ladder climbing has become a cultural tourism experience project, and the old school site that has been discontinued has been transformed into a tourist reception center, boutique homestay and hot spring, which makes the villagers very excited.

Pacha Youge is now the Party Secretary of Guri Town, where Cliff Village is located. In 2016, when we first came to Cliff Village, Pacha Youge was the first secretary in the village. In recent years, the road of Cliff Village is changing, the industry is changing, and people are also changing, but everyone’s vision for tourism development has never changed. Taking advantage of the reunion back to the village, Pacha said a few words to the villagers.

Pacha Youge told us that Liangshan Wenlv Group plans to invest 330 million yuan in the "Valley of the Sky" cultural tourism project, which will be followed by cableway sightseeing, hiking and cave exploration. This Spring Festival holiday, the first phase of the project has received more than 3,500 tourists. At present, Cliff Village has been successfully selected as the first batch of rural tourism key villages in China, and the villagers have more expectations for the future.