标签： 上海茶馆

Respiratory syncytial virus (RSV) is one of the most frequently mentioned respiratory infectious diseases or pathogens in the winter of 2023.

Last November, at the press conference organized by National Health Commission, RSV was mentioned many times. On November 13, 2023, Wang Quan, chief physician of Beijing Children’s Hospital, said, "On the whole, virus is still the most common pathogen of respiratory tract infection in children, including influenza virus, rhinovirus, adenovirus and respiratory syncytial virus." On November 26, 2023, Mi Feng, spokesperson of the National Health and Wellness Commission and deputy director of the Propaganda Department, once pointed out that "monitoring shows that recently, respiratory infectious diseases are mainly influenza. In addition, rhinovirus, mycoplasma pneumoniae, respiratory syncytial virus, adenovirus, etc. "

RSV is a negative single-stranded RNA virus belonging to the genus Pneumonia of Paramyxoviridae. It is named because it is related to respiratory tract infection and can fuse infected cells. Moreover, RSV is the pathogen of acute respiratory infection after influenza.

According to a prospective surveillance study on all-age patients with acute respiratory infection in China from 2009 to 2019, the etiology and epidemiological characteristics of about 231,000 patients were analyzed. As a whole, influenza (28.5%), RSV(16.8%) and rhinovirus (16.7%) were the most common virus pathogens. Children and the elderly are the key people infected with RSV. Among them, in children under 5 years old, the positive rate of RSV detection exceeds that of influenza and rhinovirus, and RSV has become the most common virus pathogen that causes respiratory tract infection in children.

On January 2nd, AstraZeneca and Sanofi jointly announced that the long-acting monoclonal antibody Nirsevimab/Nisevimab was officially approved for marketing in National Medical Products Administration, China, to prevent lower respiratory tract infection (LRTI) caused by RSV in newborns and infants. This also fills the gap that there is no medicine for preventing RSV infection in infants in China.

It is worth noting that nisevimab is the first and only approved preventive measure to protect infants from RSV infection in China, covering healthy full-term infants, premature infants and infants susceptible to severe RSV infection due to special health conditions. In addition, nisevimab can achieve the effect of continuous protection for 5 months with one injection, that is, a typical RSV infection season (November-April in the northern hemisphere, totaling 5-6 months).

AstraZeneca and Sanofi revealed that nisevimab is expected to be listed in China during the RSV infection season in 2024-2025. Previously, nisevi monoclonal antibody had been approved in the European Union and the United States. The listing applications submitted by nisevimab in Japan and other markets are also under review.

At present, there are two main ways to prevent RSV infection: vaccination and drug prevention. In terms of drugs to prevent infection, infants can prevent RSV infection by injecting palizumab or nisevimab, while adults have no related RSV preventive drugs at present.

Both palizumab and nisevimab are products of AstraZeneca. Among them, palizumab is the first drug approved for the prevention of RSV infection in children in the world. It was approved for marketing in the United States in 1998 and has not been approved for marketing in China yet. The population covered by this drug is small, and the EU only recommends the use of this drug for premature infants within 6 months and under 35 weeks after birth, children with bronchopulmonary dysplasia (BPD) who need treatment in the past 6 months, and children with congenital heart disease (CHD) who are over 24 months old.

Moreover, compared with only one injection of nisevizumab in an RSV epidemic season, palizumab needs to be injected once a month in the RSV epidemic season, and the drug price is high.

In terms of vaccines, in 2023, the FDA approved the listing of RSV vaccines from Pfizer and GlaxoSmithKline. Infants within 6 months can take the initiative to inoculate Pfizer bivalent RSV vaccine Abysvo at 24-36 weeks of pregnancy to prevent RSV-related lower respiratory diseases, while people over 60 years old can be inoculated with GlaxoSmithKline’s RSV vaccine Arexvy or Pfizer bivalent RSV vaccine Abysvo for prevention, and there is no relevant RSV vaccine on the market for other age groups.

At present, GlaxoSmithKline’s RSV vaccine has been approved for clinical trials in China and has reached cooperation with domestic pharmaceutical companies. On June 19th, 2023, China National Medical Products Administration Drug Evaluation Center (CDE) official website announced that the RSV vaccine (AS01E adjuvant system) declared by GlaxoSmithKline had obtained implied permission for clinical trials and was suitable for active immunization to prevent lower respiratory diseases in adults aged 60 and above caused by RSV-A and RSV-B subtypes. On October 8, 2023, GlaxoSmithKline reached a strategic cooperation with Zhifei Bio, and Zhifei Bio won the priority agency right of RSV vaccine in mainland China.

It is worth mentioning that not long ago, the only RSV vaccine giant started a patent war. In August 2023, GlaxoSmithKline filed a patent lawsuit against Pfizer, claiming that Pfizer’s RSV vaccine Abrysvo infringed four patents of GlaxoSmithKline’s vaccine Arexvy. If GlaxoSmithKline wins the case, Pfizer will be permanently banned from selling and producing RSV vaccine in the United States in the future.

RSV is considered as the next field with a market of 10 billion dollars. Minsheng Securities Research Report shows that the overall global market size of RSV drugs (including preventive and therapeutic drugs) is expected to increase from $1.8 billion in 2020 to $12.8 billion in 2030, with a compound annual growth rate of 21.4%.

The market potential of RSV can be seen from the sales of products that have been listed. The aforementioned two RSV vaccines, Abrysvo of Pfizer and Arexvy of GlaxoSmithKline, achieved revenue of $375 million and $870 million respectively in the first quarter after being approved for marketing. Insight database shows that even palizumab, which has extremely limited coverage and short effect duration, has reached a sales peak of $1.6 billion in the past decade.

Many domestic pharmaceutical companies have also joined the development of the 10 billion blue ocean market. From the domestic research and development of RSV vaccine, many pharmaceutical companies, such as watson biological/Blue Magpie Bio, Unacon, Zhifei Bio, Clover Bio, Aidiweixin, participated in the research and development of RSV vaccine, but most of them are still in the early stage. Among them, the research and development progress of Aidiweixin is relatively fast, and its product ADV110 is in the second clinical stage; It is estimated that the phase II study will be extended from the elderly group to the infant group in 2024, aiming at protecting children aged 6 months to 5 years and the elderly over 65 years old.

According to the research of children’s RSV preventive drugs, TNM001 of Tylenol Mai Bo is in phase II/III clinical research, and RB0026 of Ruiyang Biotechnology is in phase I clinical trial. In addition to the products already on the market, the fastest research and development progress in the world is Clesrovimab of Merck, which has been in phase III clinical research.

Judging from the drugs under research for the treatment of children’s RSV infection, the domestic pharmaceutical company Aike Baifa AK0529 has submitted an application for NDA registration, and the progress is leading. AK0529 is an oral drug, which is suitable for children from birth to 24 months old. In addition, RV521 from Pfizer and EDP-938 from Enanta are under research all over the world, all of which are oral drugs, suitable for children aged from January to 36 months and 28 days to 36 months respectively. As of October 20, 2023, these two products are in phase II clinical trials.

Editor’s Note: This article is from WeChat WeChat official account "Tech Planet" (ID:tech618), by Li Xiaolei, published by 36Kr with authorization.

Just like 16 years ago, Jason once again became a "crab eater" by taking part in "My Show" and becoming a champion.　

On September 21st, Netease Cloud Music officially announced that it had reached a brand-new strategic cooperation with famous musician Jason. This means that the two parties will carry out innovative operations in music copyright, personal music IP development, music works creation and online music performance. This is also the first in-depth cooperation mode between the head singer and the streaming music platform involving music copyright, personal IP, operation announcement and so on.　

Since 2004, Jason, who has been groping in the music industry, has witnessed the changes of the music industry from the record era to the streaming media era. For the head singers, the new music industry, which is slowly unfolding in front of them, has undergone tremendous changes compared with the past.　

The hard power of music streaming media platform has been extended to the comprehensive operation of musicians and music works, including the redevelopment of music copyright, concerts, IP peripheral and other diversified commercial operations.　

The cooperation with Jason is also the first shot for Netease Cloud Music to open the ∞ Unlimited Music Plan. While supporting original musicians, Netease Cloud Music has another "abacus"-through the "Infinite Music Plan", more mainstream musicians will be held in hand to provide them with a new service model based on the music platform, which will inject more vitality into new and old music.　

The combination of head singers and head music platforms will also become another competitive trend in the music industry.

From the earliest signing of Shangteng Entertainment, to Tianyu Media, and then to the independent studio, Jason, who debuted in the draft, has turned into the top male singer in the Chinese music scene and won the Grand Slam of the mainland music award. In 16 years, he released 14 music albums and left more than 200 singles.　

When Jason debuted as an amateur in 2004, it was a period of drastic changes in the music industry.

Dao Lang became a key figure in Chinese music this year. At that time, there was no concept of "sinking the market", but the first album "The First Snow in 2002" released by Dao Lang, with its unique music type, "entered" the urban and rural markets in one fell swoop, bringing about a change in music types.　

In the record era, musicians mostly earned their income by selling physical albums and records. The sales volume of Dao Lang’s first album claimed to be as high as 2.6 million. Pay-as-you-go CRBT became popular from this year, and the profit of record companies was replaced by the service fee of paying for downloading CRBT. Song Ke, who was the CEO of Taihe Wheat Field at that time, even spent tens of millions to buy out the color ring back tones copyright of Dao Lang’s three songs.　

Over the past 10 years, the mode of music announcement and profit has undergone tremendous changes. The mode of music profit has changed from records and ringtones to establishing exposure on streaming media platforms and social platforms and selling digital singles and albums. At the same time, on the basis of gaining influence, we will tour and develop and sell the surrounding IP products.　

Most mainstream head musicians came out of the era of traditional record industry, and the traditional announcement and distribution modes that prevailed in the past, such as playing charts, releasing records, signing sales tours and performing in various places, have long since fallen behind in this era.　

In the fast-paced moment, the streaming media platform has obviously become an important part of musicians’ communication channels, and the rise of Tik Tok and Aauto Quicker has also opened a new door for musicians.　

In other words, the Internet is reconstructing the traditional music industry, and the cooperation between digital music platform and record companies, brands and musicians has gradually become closer. To some extent, digital music platform plays an important role in promoting the value of the whole industry chain in the music industry.　

Jason’s hand in hand with Netease Cloud Music is clearly an insight into this trend. In fact, this is also a new mode of all-round music cooperation with head singers initiated by Netease Cloud Music.

Under this brand-new mode, Netease Cloud Music will provide multi-dimensional module services such as accurate and intelligent recommendation of works, personal music IP development, exclusive music brand activities, music linkage at home and abroad, cross-border integration of original music, offline and offline music performances, new interaction in Yuncun community, and commercial development of music content.　

For example, relying on personalized recommendation, song list, music review, Mlog and other product features, Netease Cloud Music has built a "music community" with unique vitality, which will help musicians reach users from multiple channels. In terms of music creation, in June this year, Netease Cloud Music also strategically invested in the AI Music Company "AIVA", and will develop innovative products to assist musicians in their creation in the future.

In the era of traditional records, the profit logic is to sell physical album records, relying more on obtaining exclusive copyright. Since her debut, Jason has released 14 albums, more than 200 high-quality music works and more than 40 OST golden songs. For Jason, who has left a large number of works, he can earn a lot of money only by his current copyright and concerts.　

In the era of digital streaming media, besides copyright, how to expand the rich and multidimensional vitality of music and make a music work have a longer tail value and influence has become a new proposition.　

Under this change, it is very important for musicians and platforms to change with the trend.

In April this year, the internal letter of Netease Cloud Music’s 7th anniversary mentioned that "we are witnessing the’ most civilian’ moment in China’s music history". Netease Cloud Music should complete the mission of "delivering the beautiful power of music", and "providing surprises for users", "serving musicians" and "the team should love music" are listed as the most important things.

The internal letter also emphasized that "the service for musicians should be more active, more detailed and more in place". In fact, as early as 2016, Netease Cloud Music pioneered the "Musician Index" and successively launched independent musician support programs such as "Stone Project" and "Ladder Project". Today, with 160,000 original musicians in Yuncun, it seems a natural thing to expand cooperation with mainstream artists in the head.　

In single sales, Netease Cloud Music had a cooperation example with Hua Chenyu’s "I really want to love this world" before. With the energy of the song itself and the operation of Netease Cloud Music, 45 days after its launch, the single has sold more than 16.67 million copies in Netease Cloud Music, with sales exceeding 50 million yuan, which is called "half a billion singles" by netizens.　

In addition to these figures, at present, there are more than 1 million messages in Netease Cloud Music Review Zone. More than 400,000 points were praised by the hottest comments, which is the additional significance given to the songs by Netease Cloud Music Community atmosphere. Some users talk about the background of the song in the comment area, which is a music dedicated to the depressed group, and some users talk about their own depressed experiences and get comfort in the comment area.　

For singers, tours, concerts and other large and small stage presentations are particularly important. Since Jason’s debut, she has held 61 large-scale concerts and toured more than 30 cities at home and abroad, with a total of 1.3 million people watching. In 2018 and 2019, she broke the box office record of a single concert in the Bird’s Nest for two consecutive years.

In the operation of online concerts, Netease Cloud Music has already had the experience of actually operating online performances, including LIVE on the cloud, "Fish Dining in Sodagreen" and the new solo concert of Mr.R&Beats in Wilber Pan.　

Not only that, Netease Cloud Music also took the lead in launching supporting services for paying to watch online performances. Take the online concert of the 7th anniversary of TFBOYS debut as an example. The ticket prices of online concerts are 30 yuan, 158 yuan and 860 yuan, respectively. The higher the price, the more rights and interests you can enjoy, and more products you can enjoy during the week. In the end, the record of this concert reached 786,000 simultaneous online users, which also broke the world record of online paid concerts.　

Today, online performances are gradually normalized, and offline performances complement the ecology. The importance of online performance planning and supporting services is also more prominent.　

Netease Cloud Music launched the "Infinite Music Plan", the essential purpose of which is to strengthen and innovate the deep cooperation mode with the mainstream artists in the head, and give full play to the superior resources of the music platform to carry out all-round integration with the mainstream artists in the head. Taking music as the benchmark core, we will create high-quality, personalized and topical music content.　

While releasing the potential of music IP, it is actually exploring the possibility of music cross-border.

Netease Cloud Music, while continuously supporting original musicians, has also begun to provide a new service model based on the music platform for head singers. To some extent, this is another evolution of the streaming music platform.　

However, in today’s diversified music channels, if we want to be re-recognized and maintain the popularity, it will test our ability to adapt to the operation and publicity of streaming media era more comprehensively.　

It is understood that after the cooperation between Jason and Netease Cloud Music, Netease Cloud Music will launch "Jason Music Week", which will promote many widely sung songs in Jason on the whole platform in terms of song list, cloud circle, Mlog and platform announcement.

From the user’s point of view, mastering the youth market is the key to the future for any industry. There is no doubt that Jason’s incremental audience market comes from young people. You should know that among the active users of Netease Cloud Music, the post-95 generation accounts for more than 60%. For most singers, reaching these new users, being re-recognized and liked is also an important measure to stimulate the original vitality of music.　

At the same time, the community atmosphere of Netease Cloud Music, including music reviews, Mlog, and Japanese push, will undoubtedly drive all kinds of music to find exclusive user groups, and even bring about the proliferation of quantity and the breakthrough of the circle.　

Undoubtedly, in the current music market, the music platform plays a key role in linking the upstream and downstream.　

In the past six months, Netease Cloud Music has successively reached cooperation with Ghibli, Warner Copyright, Shaocheng Times, Rolling Stone Records, Universal Music Group, Indie Works, BPMT(BPM Tokyo), CUBE Entertainment, etc. Almost every month, one or two copyright cooperation agreements have been reached, and the richness of the music library has already reached the leading level in China.　

On September 14th, Netease Cloud Music just announced that it has reached a strategic cooperation with Bertelsmann Music Group (hereinafter referred to as BMG). The two parties will carry out deep-seated and diversified cooperation in the upstream and downstream fields of music copyright, deep development of music IP, music performance, online karaoke and so on.　

Judging from the cooperation of various companies, the cooperation between Netease Cloud Music and various copyright parties is not simply the cooperation of music copyright authorization, but has expanded to more fields. Music copyright, deep development of music IP and deep operation of music performance have been repeatedly mentioned, and this cooperation mode will also become a new trend of copyright cooperation. It is no longer new to obtain music copyright alone. How to inject more three-dimensional vitality into a music work is the key to the competition of streaming media music platforms in the future.　

All these measures mean that Netease Cloud Music is exploring the deep water area of the music platform. In addition to copyright competition, the more important problem left for the music platform has become how to inspire musicians, users and industries to have greater value.　

While absorbing the head musicians headed by Jason, and providing them with high-quality music services, high-quality music content and the community ecology fed back by peripheral services, the differentiation advantage of Netease Cloud is gradually strengthened, followed by the continuous destruction of songs and music-related content. Once this closed loop of musician-content-community ecology is formed, it will undoubtedly become the competitive advantage of Netease Cloud Music in the future.　

Grasping the head musician firmly is another dimension of the music platform besides music copyright competition and user competition. In the future, how to provide more complete music operation for head musicians and independent musicians, pay attention to creation and announcement, and provide new music services will all become the new "homework" of the platform. Only by doing this problem well can you become an "excellent student" in the industry.

Let’s take a look at some basic information about this car. Needless to say, the luxury and hard-core square box of this car can provide front electric/heating/ventilation leather seats as soon as it enters the cabin, 9-speaker Swallow Lise audio and dual-zone air conditioning to ensure comfort, as well as dual 12.3-inch LCD screens and corresponding intelligent network connection system, covering intelligent voice, remote vehicle control and other interconnection functions. Coupled with blind spots and panoramic chassis images, L2-level assisted driving in the middle of the lane, and+fog lights to ensure all-weather driving, its functionality is still outstanding.

In terms of mechanical hardware, it is equipped with a 2.0T turbocharged engine, with a maximum power of 167kW and a maximum torque of 387 N m. It will be matched with ZF 8AT gearbox and part-time 4wd system to realize torque amplification. In addition, it also has front and rear double differential locks, and supports low-speed four-wheel drive, tank turning and other functions. The passing capacity of various road conditions can be seen.

In terms of insurance cost, we calculated the bare car price as 216,800 yuan, including major commercial comprehensive insurance (excluding additional insurance such as glass insurance/water crossing insurance/spontaneous combustion insurance/theft insurance) and compulsory insurance. The insurance cost of the vehicle in the first year is about 6,901 yuan. Based on the calculation of 60,000 kilometers in three years, 10% discount in the second year/20% discount in the third year, the average insurance cost in the first three years is about 6,211 yuan/year.

In terms of maintenance cost, the maintenance frequency of tank 300 is 7500 km/time, 5000 km/time and 12500 km/time. The first two maintenance are free, including 1 brake oil, 1 gearbox oil, 1 antifreeze and 2 spark plugs. The oil and oil filter are replaced every time, and the air conditioner/air conditioner/gasoline filter is replaced every other time. In the first three years, the total maintenance cost of 60 thousand kilometers was about 2992 yuan, and the average annual maintenance cost was about 997 yuan/year.

In terms of fuel cost, the WLTC comprehensive fuel consumption of tank 300 is 9.90L/100km. According to the current average price of No.92 gasoline of 8.48 yuan /L, we calculate that the average fuel cost of 60,000 km in the first three years is about 16,790 yuan/year.

Together with insurance, maintenance, fuel and annual vehicle and vessel tax, the main vehicle cost of Tank 300 is about 24,398 yuan a year, that is to say, the vehicle maintenance cost will reach 2,033 yuan a month, which is actually very close to the compact or medium-sized luxury SUV equipped with a 2.0T engine, which may be the price of pursuing off-road driving in various road conditions.

Nevertheless, the cumulative sales volume of Tank 300 in the first eight months of 2023 has reached 62,240 units, and the average monthly sales volume has reached 7,780 units, which fully demonstrates the continuous competitiveness of the car in the market. In addition, it is worth mentioning that the tank 300 does maintain its core competitive advantage in power performance and multi-road driving ability, and at the same time, it also meets the needs of urban drivers in terms of intelligence and comfort through a series of luxury configurations. How can such a comprehensive hard-core off-road vehicle not make people "love and hate"?

??important news

??July new power list: after 7 months, the ideal to break 50,000 new high, ask the world, and polar krypton sales decline

First Electric reported on August 1 that the new forces announced the July delivery record as scheduled. After a lapse of 7 months (50,353 vehicles were delivered in December last year), the ideal sales volume once again exceeded 50,000 vehicles to 51,000 vehicles, a record high, and won the championship of the new power list for two consecutive months. After breaking through 20,000 vehicles in June, the sales volume in July broke through 20,000 again to 22,093 vehicles, setting a new record high, surpassing NIO again and ranking fourth on the list. Extreme krypton, Q-world and NIO sales fell month-on-month in July, of which Extreme krypton sales fell by 22%, NIO and Q-world sales fell slightly by 3.4% and 2.9% respectively. Avita, a subsidiary, has not announced sales as of press time. Deep Blue sold 16,721 units in July, ranking sixth.

??July sales 342,400, an increase of 30.6%

BYD shares on August 1Announcement, in July 2024, the production of new energy vehicles was about 320,900, an increase of 17.78% year-on-year; sales were about 342,400, an increase of 30.6% year-on-year. It is worth noting that the sales of plug-in hybrid models 193,500 in July, significantly exceeding the sales of pure electric models (125,800), the difference has been nearly 70,000. The ratio of the two quantities has also come to 1.54:1. Subsequently, the official account of Difan Home announced,In July, BYD passenger cars sold a total of 340,799 vehicles, including 172,930 Dynasty Network models, 152,767 Ocean Network models, 439 Yangwang brand deliveries, 1,842 Equation Leopard brand deliveries, and 10,340 brand deliveries. BYD Qin L sold 32,000 vehicles, and 06 sold 25,000 vehicles.

From January to July 2024, the production of new energy vehicles was about 1.9529 million, an increase of 26.16% year-on-year; the sales volume was about 1.9554 million, an increase of 28.83% year-on-year. The company sold a total of 30014 new energy passenger vehicles overseas in July 2024. The company’s total installed capacity of new energy vehicle power batteries and energy storage in July 2024 was about 16.519GWh, and the cumulative installed capacity in 2024 was about 89.075GWh.

??Car sales in July 91,300 units, down 16.32% year-on-year

Great Wall Motor announced on August 1 that the total sales volume in July was 91,285 units, down 16.32% year-on-year; the cumulative sales volume this year was 650,954 units, an increase of 3.60% year-on-year. Among them, 24,145 new energy vehicles were sold in July, and 156,519 units were sold in January-July.

Of the brands under the Great Wall, only the tank brand achieved a year-on-year positive growth (+ 77.26%), and the rest of the brands declined year-on-year. Among them, the pure electric brand Euler decreased by 42% year-on-year, and the Great Wall pickup also decreased by 13.86% year-on-year.

??July sales 150,800, up 13% year-on-year

August 1st news,Geely AutomobileThe latest production and sales data revealed that car sales in July were 150,782 units, an increase of 13% year-on-year. Geely Automobile exported 32,382 units in July, an increase of 65% year-on-year.Brand sales reached 113,855, an increase of 9% year-on-year, of which 16,704 units of the Galaxy series increased by 66% year-on-year.Car sales in July reached 21,272 units, an increase of 24% year-on-year; Extreme Krypton vehicles 15,655 units, an increase of 30% year-on-year. Geely Automobile sold 28,193 plug-in hybrid vehicles in July, an increase of 119% year-on-year; JulySales were 30,858 units, an increase of 26% year-on-year.

??The Group’s July automobile sales 196,000 increased by 30.1% year-on-year, and new energy increased by 254.5% year-on-year.

On August 2, Chery Holding Group released sales data for July 2024, selling 195,759 vehicles in July, an increase of 30.1% year-on-year. Chery brand: sales of 123,123 units in July, an increase of 20.4% year-on-year; sales of 829,890 units in January-July, an increase of 38.3% year-on-year; Xingtu brand: sales of 14,443 units in July, an increase of 26% year-on-year; sales of 68,890 units in January-July, an increase of 28.3% year-on-year; brand: sales of 41,106 units in July, an increase of 91.1% year-on-year; sales of 264,661 units in January-July, an increase of 97.7% year-on-year; iCAR brand: sales of 6065 units in July after the first product was launched for 5 months; cumulative sales of 31,651 units since the beginning Chery Group exported 90,281 vehicles in July, an increase of 16.8% year-on-year; new energy sales of 45,370 vehicles, an increase of 254.5% year-on-year. From January to July, Chery Group sold a total of 1296,380 vehicles, an increase of 45.4% year-on-year.

??MIIT: Before enterprises implement OTA upgrade activities, they should ensure that automotive products meet relevant requirements and file

On August 1, MIIT publicly solicited opinions on the "Notice on Further Strengthening the Management of Access, Recall and Software Online Upgrade of Intelligent Connected Vehicles" (exposure draft). It pointed out that the supervision and management of OTA upgrade activities should be strengthened. Before implementing OTA upgrade activities, enterprises should ensure that automotive products comply with relevant requirements such as national laws and regulations, technical standards and technical specifications, and file with the Ministry of Industry and Information Technology and the General Administration of Market Supervision according to relevant requirements. The filing content includes enterprise management capabilities, models and functions, specific upgrade activities and relevant certification materials. Enterprises can only carry out OTA upgrade activities after the filing is completed. Those involving changes in product technical parameters should be reported to the Ministry of Industry and Information Technology before filing to ensure the consistency of automobile product production. The State Administration for Market Regulation shall conduct filing evaluation and supervision inspections in a timely manner, standardize the application methods of OTA upgrades, and prevent enterprises from concealing vehicle defects or evading responsibilities through OTA upgrades. Those who use OTA upgrades to eliminate automobile product defects and implement recalls shall formulate a recall plan in accordance with the Implementation Measures for the Regulations on the Administration of Recall of Defective Automotive Products, and file with the State Administration for Market Regulation in a timely manner.

??Sharp comment on BYD’s cooperation with Uber: BYD needs to change its route as soon as possible, otherwise it will be troublesome

On August 1st, Uber, the originator of online ride-hailing, announced that it will cooperate with BYD to add 100,000 electric vehicles to the platform. The cooperation will be launched first in Europe and Latin America. It is expected to provide first-class pricing and financing services for BYD car drivers on the Uber platform, and will expand to markets such as the Middle East, Canada, Australia and New Zealand. In addition, the two sides will also cooperate to develop future BYD cars and deploy them on the Uber platform. CEO Musk also paid attention to this matter, and immediately issued his own sharp comment, saying: BYD needs to change course quickly, otherwise it will be in trouble. Why did Musk suddenly have such a statement? That’s because the media quoted Li Yunfei, the general manager of BYD’s brand and public relations department, in the article reporting the cooperation between BYD and Uber, that "fully autonomous driving is basically impossible." Obviously, Musk does not agree with this view at all. After all, Tesla’s ultimate goal is fully autonomous driving. Musk said earlier this year that he would launch a special taxi on August 8, and in the earnings call, Musk also said that the release date would be delayed to October 10.

??domestic

??Avita 07 design details announced

IT Home reported on August 1 that Avita officially announced the design details of Avita 07 car today, continuing the family-style front face, adopting a low wind resistance design, and a comprehensive battery life increase of 46.2 kilometers.

The car will provide two different kinds of power: extended range and pure electric. It will be pre-sold in the third quarter of this year (this quarter) and is expected to be officially launched in September. Its length, width and height are 4825/1980/1610 (or 1620) mm respectively, and the wheelbase is 2940mm. The pure electric model can choose 252kW single motor and 188 + 252kW dual motor. The extended range model is equipped with a 1.5L range extender of 115kW, and can choose 231kW single motor or 131 + 231kW dual motor.

The cockpit of the car adopts a wrapping design and uses a four-screen arrangement (an integrated super-long "hairtail screen", a horizontal central control screen, and two secondary screens at the edge for streaming media external rearview mirrors); the front seats are all zero-gravity seats, made of Nappa leather, and the right side of the main driver is equipped with mobile phone wireless charging, cup holder, etc., and provides a physical car key.

There are 39 ambient light sources in the whole car, and the longest is equipped with 2854mm continuous light strips; the peak power of the speakers in the car is 2016W, and the tuning technology of "British Treasure" is used to support 7.1.4 channel rendering composed of "four-way sky sound".

??Ledao is fully integrated into the NIO service system

Electric Zhijia reported on August 1 that NIO’s Ledao Automobile will be officially listed in September. Everyone is curious. Will the "service" that NIO has always been proud of be reflected in Ledao? What is the relationship between Ledao and NIO’s service? Ledao Automobile officials explain this.

Ledao Auto said that Ledao services are fully integrated into the NIO service system and share the NIO service network. It is expected that by the end of 2024, more than 350 NIO service centers in 200 cities across the country will have the repair and maintenance capabilities of Ledao cars. In the future, we will continue to expand the service network according to user requests, and open Ledao brand exclusive service stores in suitable areas.

NIO’s most distinctive one-click maintenance, door-to-door tire repair, maintenance and car delivery services will also serve Ledao users. The Ledao service package is more lightweight than the NIO service package. In September, the policy, pricing, and detailed interpretation of rights and usage instructions will be announced. If NIO’s service is worry-free throughout the process, then Ledao’s service is flexible and efficient. From the service center to the service staff, from the service process to the service standard, Ledao will continue the quality and experience of NIO’s service, but it will be defined differently in service products.

??Lynk & Co 09 MHEV 4WD Global Edition model price reduction for a limited time 30,000

IT Home August 1st news, Lynk & Co Automobile announced today that the Lynk & Co 09 MHEV four-wheel drive global version will launch a "limited-time exclusive price" from now on, priced at 235,800 yuan (previously the official guide price was 265,800 yuan).

At the same time, the car can also enjoy comprehensive car purchase rights of up to 40,000 yuan this month, including 15,000 yuan purchase tax, 10,000 yuan replacement/additional purchase subsidy, 5,000 yuan to the store purchase subsidy, up to 10,000 yuan financial subsidy.

IT Home news on August 1, Zhang Zhuo, general manager of BYD Ocean Network Sales Division, posted on the social platform that BYD Seal EV will retain the original "Seal" name without change; while the hybrid model equipped with the fifth generation DM-i technology will be named Seal 07DM-i. The official appearance map of the new car was also announced, and the color scheme was named "Sky Purple".

??Beijing promotes "oil-for-electricity" and "oil-for-hydrogen" for public and social sector vehicles

On August 1, the Beijing Municipal Committee of the Communist Party of China and the Beijing Municipal People’s Government issued a statement on building a beautiful Beijing in an all-round way and accelerating the harmonious coexistence of man and natureImplementation opinions of transformation. Among them, it is proposed to optimize the transportation structure, improve the "package" support policies such as strong new energy automobile industry, additional application, promotion of consumption, and favorable traffic, accelerate the construction of facilities such as charging and exchanging electricity, hydrogen refueling stations, and promote the "oil-for-electricity" and "oil-for-hydrogen" of vehicles in public and social fields. Promote the green transformation of railway stations, civil airports, logistics parks, etc., and build a clean transportation fleet. Vigorously promote the green development of buildings, focusing on the construction of ultra-low energy consumption buildings and the energy-saving and green transformation of existing public buildings, promote the low-carbon green transformation of heating, and promote the integration of photovoltaic buildings and other technical applications By 2027, natural gas consumption will decline steadily, gasoline and diesel consumption will continue to decline, and renewable energy consumption will account for about 20%; by 2035, natural gas and gasoline and diesel consumption will decrease significantly, and renewable energy consumption will account for 35%.

??Chinese Statement on Japanese Certification Application: Compliance with Chinese Quality Standards

On August 1, IT Home quoted NHK as reporting yesterday that Japan’s Ministry of Land, Infrastructure, Transport and Tourism has decided to issue a correction order in the near future under the Road Transport Vehicles Law, requiring automakers and others to completely reform the issue of "model certification" necessary for the mass production of automobiles and other vehicles in violation of regulations, and saidNew irregularities discovered by Toyota Motor Corporation…

Toyota China issued a statement today in response to the incident, expressing its sincere apologies for the concerns that some models of the same name may have caused to Chinese customers. Toyota China said that after confirmation, the relevant certification experiments of FAW Toyota, GAC Toyota and models sold in the Chinese market were completed in strict accordance with Chinese laws and regulations, under the supervision and guidance of the Chinese management department, and met the national quality-related standards. There are no safety and quality problems. Please feel free to use them.

??SAIC-GM sold 44,800 vehicles in July

On August 1, SAIC General Motors released sales data for July. In July 2024, SAIC General Motors retail sales were 44,822 units, an increase of 2% compared with the previous month. Among them, the retail sales of new energy vehicles were 7,901 units, an increase of 27% compared with the previous month. From January to July 2024, the cumulative retail sales were 349,922 units. Among them, the cumulative retail sales of new energy vehicles were 50006 units, an increase of 41.6% year-on-year. Specifically,GL8’s retail sales in July were 8,229 units, an increase of 53% month-on-month, reaching the top in a rowWeekly sales list.

??Yipai sold 6,329 units in July

On August 1, Dongfeng Yipai official blog announced that from March 14, Yipai 007 was listed, and as of July 31, a total of 23,157 units had been sold, and the sales volume in July was 6,329 units. Dongfeng Yipai eπ 007 extended range version was listed and delivered on August 9. Eπ 008 was officially listed and delivered on June 14, and the sales volume exceeded 8,000 units in one and a half months of listing.

??FAW Toyota sold 70,200 vehicles in July, and the new generation Prado was delivered on August 5

August 1st news, FAW Toyota today announced the latest delivery data for July: 70,165 vehicles delivered in the month. FAW Toyota delivered 73,545 vehicles in June. The official delivery data was not released in July last year. It can be seen that FAW Toyota’s delivery in July this year fell slightly by 4.6% month-on-month, but still exceeded 70,000 vehicles. At the same time, the new generation Prado will officially start delivery on August 5th. The car has been listed and rolled off the assembly line. A total of 4 models have been launched, and the price range is 45.98-54 9,800 yuan.

??New generation EQA pure electric SUV and EQB pure electric SUV launched

On August 1, Mercedes-Benz officially announced that the new EQA pure electric SUV and EQB pure electric SUV were officially launched, launching a total of three models: EQA260 pure electric SUV, EQB 260 pure electric SUV and EQB3504MATIC pure electric SUV, with recommended retail prices of RMB 322,000, RMB 352,000 and RMB 428,000 respectively.

??Avita released the latest limited-time car purchase rights, value 64,000 configuration free upgrade

On August 1, Avita officially released the latest car purchase rights, including the followingYou can enjoy free equipment upgrades worth 64,000 yuan; if you order Avita 12, you can enjoy hardcore upgrades worth 42,000 yuan. The event starts from now until August 31.Specifically, from now until August 31st, when you order Avita 11, you can give away a British treasure audio set worth 30,000 yuan for a limited time, as well as a front-row double zero-gravity seat worth 15,000 yuan, and a smart fragrance system worth 3,000 yuan. Optional Twilight Purple/Smoke White interior can be reduced by 10,000 yuan, and the black car color worth 6,000 yuan is free for a limited time. Order Avita 12 and you can also enjoy an upgrade gift worth 42,000 yuan, including 20,000 yuan of optional accessories and 22,000 yuan in cash. For details, please consult your local dealer.

??It is reported that Su Tan, the former general manager of Baidu IDG’s automotive business department, has joined Microsoft Cloud to form a new automotive team

On August 1, Leifeng.com New Intelligent Driving reported that Su Tan, general manager of Baidu IDG (Intelligent Driving Business Group) Automotive Business Department, who left in early July, joined Microsoft Cloud and reported to Yuan Xin, president of Microsoft China. Microsoft Cloud China previously had a low-level automotive team within the EC (Enterprise Business) department. After Su Tan arrived, Microsoft established a separate automotive team for it, which was on par with the EC department, and the strategic height of the automotive business was improved.According to the news, the formation of the newly established automotive team has not been fully determined, but the AE post of the original automotive team has been greatly downsized. In the past year, two executives of IDG have joined the cloud manufacturer. In early October 2023, the general manager of Baidu ASD (Intelligent Vehicle Division), who was also Su Tan’s boss at Baidu, Chu Ruisong, took over the No. 1 position in AWS Greater China. Not long ago, Chu Ruisong made personnel adjustments to the AWS automotive industry line. The former head of the company, Ji Jun, left, and Chu Ruisong’s former Baidu subordinate, Zhao Yi, succeeded him.

??Extreme Krypton and Israeli autonomous driving company Mobileye will accelerate the localization of technology in China

Extreme Krypton Automobile and Israeli autonomous driving technology company Mobileye announced on August 1 that they plan to accelerate technology localization in China and integrate Mobileye SuperVision technology into next-generation Extreme Krypton models. Extreme Krypton plans to expand the installation range of the Mobileye SuperVision platform to more vehicles and further expand the highway and city coverage of its existing ZEEKR Pilot system.

??Former executives "cloned" to start a business? Guoxuan Hi-Tech responded: The news is not true

On August 1, according to a report by 21 Economic Network, recently, an article titled "Guoxuan Hi-TechThe former executives of the company are cloning another Guoxuan Hi-Tech! "The article attracted attention in the industry. According to public information, Hu Xiaoming, the legal representative and largest shareholder of Guoxuan Energy, Fang Jianhua, the second largest shareholder, and Wang Chenxu and Yang Xulai, the shareholders, were all executives or shareholders of Guoxuan Hi-Tech. In this regard, the reporter checked with Guoxuan Hi-Tech as an investor, and the relevant staff responded:" The news is not true, and there is no relationship between the company and Guoxuan Energy. "The person further said that the news has been fermented on the Internet, and the company has paid attention to it and will consider reporting false news. When asked whether the executives signed a non-compete agreement, the above-mentioned staff said they were unsure of the situation and needed further verification, but the staff did sign a non-compete agreement when they joined the job.

??international

??Tesla’s 10 million electric drive system released, a new milestone moment

On August 1, Tesla officially announced that the world’s 10 million electric drive system was rolled off the production line at Tesla’s Shanghai Super Factory, which is the first "10 million" milestone reached by Tesla. Tesla’s electric drive system is all self-developed and self-produced by Tesla from scratch. Integrating the motor, gearbox and motor controller, it is the powerful heart of Tesla electric vehicles, bringing the iconic "Tesla power" to each car. Data shows that Tesla can currently roll off an electric drive system every five seconds worldwide. Tesla official said in Weibo: "Tesla redefines the electric drive system, self-developed and self-produced from scratch, more than 10 million powerful" hearts ", making Tesla all performance cars. Thanks to the support and company of more than 6 million car owners, together we accelerate the world’s transition to sustainable energy. "

??Sales of South Korea’s top five automakers fell 2.2% year-on-year in July, falling for three consecutive months

According to the sales performance released by South Korea’s five major vehicle manufacturers on August 1, the total sales volume of Korean-made automobiles at home and abroad (including full parts assembly) decreased by 2.2% year-on-year in July, which was 658,297 vehicles.

Specifically, due to the high sales base in the same period last year, the domestic sales of the five major automakers experienced negative growth for six consecutive months, falling 4.1% in the month to 110,152 vehicles; overseas sales fell 1.8% year-on-year to 548,145 vehicles. This was mainly due to factors such as the temporary stagnation of electric vehicle market demand in Europe and Asia Pacific, which led to a decrease in export traffic. According to automakers, Hyundai Motor sold 332,003 vehicles, down 1.4% year-on-year; 261,334 vehicles were sold, up 0.2% year-on-year; General Motors of Korea sold 51,200 vehicles, down 14.8% year-on-year; KGM (formerly automobile) sold 8,313 vehicles, down 23.4% year-on-year; South Korea sold 5,447 vehicles, up 12.7% year-on-year.

??The two companies will deepen cooperation in the fields of software, batteries and "E-Axle"

On August 1, Honda, Nissan and Automotive signed a memorandum of understanding that will begin discussions on a strategic cooperation framework for intelligent and electrified vehicles. Honda and Nissan announced on August 1 that the two sides reached a joint research agreement on basic element technologies in the field of next-generation software-defined vehicle platforms, and signed a memorandum of understanding on deepening strategic partnership in the field of technologies such as batteries and electric vehicle drive units "E-Axle". Under the new agreement, Mitsubishi will join the discussions between the two companies.

??Auto sales in the second quarter 36.944 billion euros, down 0.7% year-on-year

On August 1, the BMW Group released its second quarter results report. The report shows that sales in the second quarter of 2024 36.94 billion euros, a decrease of 0.7% year-on-year, of which the second quarter automotive division revenue 32.07 billion euros, an increase of 1.4% year-on-year. The second quarter EBIT 3.88 billion euros, a decrease of 10.7% year-on-year. Deliveries in the second quarter were 618,743 vehicles, a decrease of 1.3% year-on-year. According to the report, the EBIT margin of the BMW automotive business was 8.4%, a decrease from 9.2% in the same period last year and lower than the market estimate of 8.75%. Specific to sales volume, in the first half of this year, the BMW Group delivered a total of 1213,276 BMW, and Rolls-Royce brand cars in the global market, which is roughly the same as in 2023. The BMW brand sold 109,423 vehicles in the first half of the year, an increase of 2.3% year-on-year. Of these, nearly 180,000 BMW brand models (179,500) were delivered worldwide, an increase of 34% year-on-year.

??Automotive second quarter revenue 83.34 billion euros, up 4.1%

Fast technology news on August 1st, Volkswagen announced today that the second quarter of 2024 revenue 83.34 billion euros (currently about 651.738 billion yuan), an increase of 4.1%, estimated 81.92 billion euros. Volkswagen’s second quarter operating profit 5.46 billion euros (currently about 42.698 billion yuan), a decrease of 2.4% year-on-year, estimated 5.17 billion euros; automotive sector operating cash flow 8.40 billion euros (currently about 65.69 billion yuan), an increase of 36%, estimated 7.41 billion euros. Volkswagen delivered 2.244 million vehicles globally in the second quarter of 2024, down 3.8% year-on-year; 4.348 million vehicles delivered in the first half of the year, down 0.6% year-on-year.

??Haobo SSR overseas version offline, delivered to South East Asia market in August

Fast Technology reported on August 1st that the overseas version of Haobo SSR has been officially rolled off the assembly line. The overseas version of Haobo SSR is expected to be delivered to the South East Asia market in August, and plans to further expand to the Middle East, South America and European markets to accelerate its high-end globalization process. The design of Haobo SSR adopts a wedge-shaped design, and the whole car has sharp lines, showing a strong fighting atmosphere. After wind tunnel testing, the vehicle has added a number of aerodynamic designs to make the aerodynamic performance reach the level of F1 racing cars. In terms of power system, Haobo SSR is equipped with a two-speed four-in-one high-performance motor, equipped with a 900V high-voltage silicon carbide chip and a full-stack self-developed Edrive 3.0 intelligent control system, achieving a maximum efficiency of 94.5% of the electric drive assembly. The three motors together provide a maximum power of over 900kW and a maximum torque of 12000N · m on wheels, enabling the vehicle to achieve zero-hundred acceleration in 1.9 seconds.

??Land Rover plans to spend an additional 3 billion pounds, aiming to electrify all models within ten years

Jaguar Land Rover, the British luxury SUV maker, announced plans to spend an additional 3 billion pounds ($3.80 billion) to support its strategic shift to the electric vehicle market. The automaker plans to increase its investment to 18 billion pounds over the next five years, with the goal of making all models fully electric by the end of this decade.

Richard Molyneux, Jaguar Land Rover’s chief financial officer, has revealed that the company will flexibly adjust its product development strategy according to the level of acceptance of pure electric vehicles in the global market and the speed of transition. This means that JLR may need to continue to develop internal combustion engines and models in some markets to meet the needs of different regions.

Zaha

Famous for Vitra Fire Station

　　Zaha Hadi, a world-renowned British architect of Iraqi origin, died at 65 of a heart attack while being treated for bronchitis at a Miami hospital, according to a BBC report. She was known as the "witch" of architecture. She had four projects in Beijing: Wangjing SOHO, Galaxy SOHO, Lize SOHO and the new airport’s Terminal 1.

　　Died suddenly in the hospital

　　Zaha Hadid Architects confirmed her death on its Web site, which said she had contracted bronchitis earlier this week and had suffered a heart attack while being treated at a hospital. She died suddenly on the morning of March 31 local time. After the news of her death broke, the architects’ Web site was repeatedly busy and inaccessible.

　　Extremely famous in the architectural world

　　Zaha is well-known in international architecture, having become the first female architect to win the Pulitzer Prize in 2004, says Frank Gehry, a jury judge. "The 2004 winner is probably one of the youngest to win and one of the clearest designs I have seen in years. Her work is full of passion and innovation." Last year, Zaha became the first female architect to win the Royal Gold Medal, the highest award in British architecture, from the Royal Institute of British Architects.

　　Zaha has designed many well-known architectural works around the world, such as the New National Arena in Tokyo, the BMW Central Building in Germany, the London Olympic Swimming Pool in the United Kingdom, the Abu Dhabi Performing Arts Center, the Innsbruck Cable Car Station in Austria, the Fino Science Center in Wolfsburg, Germany, the Cincinnati Center for Contemporary Art in the United States, and the 170-meter glass tower in Milan.

　　In Beijing, Zaha’s work includes New Airport Terminal 1, Wangjing SOHO, Galaxy SOHO, and Lize SOHO.

　　Zhang Xin, chief executive of Soho China, also wrote on Weibo last night: "I just received the shocking news that my good friend Zaha Hadid, an architect, died of a heart attack this morning in Miami. Seeing her in New York last week, I didn’t expect her to be the last of us."

　　Zaha’s employee, Chinese architect Shen Jianghai:

　　Her temper is just critical of the design itself

　　"She has influenced almost everyone who does architectural design," Shen Jianghai, a Chinese architect and former employee of Zaha, told reporters in the morning. Since she was 19 years old and a freshman in college, Zaha has been her most admired architect, and this worship has continued to this day. It has not changed for more than a decade, and no designer can replace it. "It was Zaha who let me know that architecture can be different, and it was also she who taught me from my freshman year how important it is for designers to persevere!"

　　Shen Jianghai said that in June 2010, he was fortunate enough to get an interview with Zaha Architects and then went to work there. During his working days, everyone worked in a small house that used to be renovated by a girls’ school, so they were able to see her often. Although Zaha’s temper is not very good, it does not affect the charm of a designer at all, and she is usually very gentle, and her temper is only critical of the design itself. "In fact, at that time, I felt that her physical condition was not very good."

　　Controversies are also her charm

　　Mr. Shen said it was not unusual for Mr. Zaha’s architectural work to be the subject of controversy online a few years ago over his project in Beijing, which was described by some as "the curve of God and the waves of heaven" and others as ugly.

　　"The controversy about Zaha is not limited to China. In fact, the world has been full of controversy about Zaha since she was discovered by Japanese architect Isozaki after her first project. But this is also the charm of Zaha, because she has led architectural design to a completely different field. Without her persistence and even paranoia, people would not know that architecture can also be streamlined." Shin Jianghai said that what he admires most about Zaha is her criticism of reality and her non-conformity.

　　Talking about Zaha and China, in Shen Jianghai’s observation, he felt that Zaha was very interested in China, and not just in the market. "In addition, she sometimes invites colleagues to eat, and she also likes to go to an expensive Chinese restaurant near Chinatown."

　　Today, the Architect’s Moments are filled with tributes to Zaha. As Shen Jianghai said, without Zaha, he would not be who he is today, and his designs would not be what they are today. "Please go all the way, many people say, you led mankind to a new world, and then you returned to your planet."

　　character life

　　The road to fame is full of thorns

　　Zaha was born in 1950 in Baghdad, the capital of Iraq, into a wealthy, enlightened family. Her parents believed in the independence of education, and they invested a lot of expectations in their daughter. Her father’s son, a close friend, was a brilliant architect, and the brother next door had a great influence on the young Zaha.

　　In 1982, Zaha won the first prize in an international architectural competition held in Hong Kong, China, strengthening her belief in continuing in this field. However, Zaha’s work was rejected in the first review. It was Japanese architect Shin Isozaki who had the unique eyes to fish her plan out of the waste paper pile.

　　Zaha was so inspired that she taught at Harvard, Yale and other prestigious universities, and her design works cover almost all design categories, including doors and windows, furniture, sculpture ornaments, lamps, chairs, water glasses and tableware. Her paintings are even more avant-garde and have been exhibited all over the world. Her works are permanently collected by industry authorities such as the Museum of Modern Art in New York and the Deutsches Architecture Museum in Frankfurt.

　　Ms. Zaha’s path to fame was fraught with thorns. Despite her early reputation as a "master deconstructionist," and despite her bold use of geometry and the many awards she has won, sometimes as many as four a year, many people still reject her bizarre designs.